The metabolism of L-fucose. II. The enzymatic cleavage of L-fuculose 1-phosphate.
The metabolism of L-fucose. II. The enzymatic cleavage of L-fuculose 1-phosphate.
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L-岩藻糖的代谢。
DOI：
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发表时间：
1962
影响因子：
4.8
通讯作者：
E. Heath
中科院分区：
文献类型：
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作者：
M. A. Ghalambor;E. Heath
催化此反应的酶，即L - 岩藻糖 - 1 - 磷酸醛缩酶，显然不同于己糖二磷酸醛缩酶。例如，由L - 岩藻糖 - 1 - 磷酸醛缩酶形成或裂解的酮糖 - 1 - 磷酸必须在C - 3和C - 4位具有顺式构型的羟基。黄和米勒（4）提出的L - 岩藻糖 - 1 - 磷酸最初在碳3位发生差向异构化生成6 - 脱氧 - L - 山梨糖 - 1 - 磷酸，而后一种物质被己糖二磷酸醛缩酶裂解的观点，未得到本文所提供证据的支持。
The enzyme that catalyzes this reaction, n-fuculose l-phosphate aldolase, is clearly distinct from hexose-diphosphate aldolase. For example, the ketose l-phosphates that are formed or cleaved by L-fuculose l-phosphate aldolase must possess hydroxyl groups at C-3 and C-4 in the cis configuration. The contention of Huang and Miller (4) that L-fuculose l-phosphate is initially epimerized at carbon 3 giving 6-deoxy-L-sorbose l-phosphate, the latter being cleaved by hexose diphosphatealdolase, is not supported by the evidence presented in this paper.