Sudden myelopathy secondary to therapeutic total-body hyperthermia after spinal-cord irradiation.
Sudden myelopathy secondary to therapeutic total-body hyperthermia after spinal-cord irradiation.
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脊髓照射后全身热疗继发的突发性脊髓病。
DOI：
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发表时间：
1981
影响因子：
158.5
通讯作者：
J. Bebin
中科院分区：
文献类型：
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作者：
M. A. Douglas;L. Parks;J. Bebin
热疗是一种新的治疗方法，在肿瘤治疗中越来越受到临床的重视。它的疗效已经在动物身上得到了很好的证明，但它的适应症、禁忌症和癌症治疗的合适地点尚未确定。1 2 3 4我们报告了3例在前两个月内脊髓照射后体温过高的急性脊髓病患者。1例尸检发现与长期照射所致的脊髓病相似。以前已经报道过全身热疗的几种神经系统副作用--最常见的是周围神经病变，但不是脊髓病。1 2 3热疗在癌症中的作用机制。
HYPERTHERMIA is a new method of treatment receiving increasing clinical attention in cancer therapy. Its efficacy has been well demonstrated in animals, but its indications, contraindications, and appropriate place in cancer therapy have yet to be defined.1 2 3 4 We report three cases of acute myelopathy in patients undergoing hyperthermia after spinal-cord irradiation within the preceding two months. Post-mortem examination in one case revealed findings similar to those seen in myelopathy resulting from long-term irradiation. Several neurologic side effects have been reported previously with total-body hyperthermia — most commonly peripheral neuropathy, but not myelopathy.1 2 3 The mechanism of action of hyperthermia in cancer . . .