EFFECTS OF CALCIUM SUPPLEMENT THERAPY IN WOMEN WITH PREMENSTRUAL SYNDROME
EFFECTS OF CALCIUM SUPPLEMENT THERAPY IN WOMEN WITH PREMENSTRUAL SYNDROME
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DOI：
10.1016/s1028-4559(09)60271-0
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发表时间：
2009-06-01
影响因子：
2.1
通讯作者：
Ashrafi, Maryam
中科院分区：
文献类型：
--
作者：
Ghanbari, Zinat;Haghollahi, Fedieh;Ashrafi, Maryam
目的：科学证据表明，各种营养物质的周期性波动，特别是钙，可能有助于解释经前综合征（PMS）的一些特征。我们确定了钙补充剂在妇女患PMS.Materials和Methods的疗效：双盲临床试验的目的是评估钙补充剂治疗对PMS症状的影响。研究小组是根据经前综合症标准从年轻女大学生中选出的。受试者被分为两组;一组接受安慰剂，另一组接受500毫克碳酸钙，每天两次，持续3个月。使用标准问卷评估症状的严重程度和强度，包括早期疲劳、食欲变化和抑郁。治疗前后的症状进行了比较。结果：平均年龄为21.4 ± 3.6岁。早期疲劳，食欲的变化，抑郁症状显着改善组接受钙治疗相比，安慰剂group.Conclusion：我们的研究结果表明，钙补充剂减少早期疲劳，食欲的变化，抑郁症的妇女经前综合征。[台湾妇产科杂志2009;48（2）：124-129]
Objective: Scientific evidence suggests that cyclic fluctuations in a variety of nutrients, especially calcium, may help to explain some features of premenstrual syndrome (PMS). We determined the efficacy of calcium supplementation in women suffering from PMS.Materials and Methods: A double-blind clinical trial was designed to evaluate the effect of calcium supplement therapy on PMS symptoms. The study groups were selected from young female college students, based on PMS criteria. The subjects were divided in two groups; one group received placebo and the other received 500 mg of calcium carbonate twice daily for 3 months. The severity and intensity of symptoms, including early fatigability, changes in appetite, and depression, were evaluated using a standard questionnaire. Symptoms were compared before and after treatment.Results: The mean age was 21.4 +/- 3.6 years. Early tiredness, appetite changes, and depressive symptoms were significantly improved in the group receiving calcium treatment compared with the placebo group.Conclusion: Our results showed that calcium supplements reduced early fatigability, changes in appetite, and depression in women with PMS. [Taiwan J Obstet Gynecol 2009;48(2):124-129]