Ventricular fibrillation in a patient with prominent J (Osborn) waves and ST segment elevation in the inferior electrocardiographic leads: A Brugada syndrome variant?

Ventricular fibrillation in a patient with prominent J (Osborn) waves and ST segment elevation in the inferior electrocardiographic leads: A Brugada syndrome variant?
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DOI:
10.1111/j.1540-8167.2000.tb00743.x
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发表时间:
2000-01-01
影响因子:
2.7
通讯作者:
Marinchak, R
Marinchak, R
中科院分区:
医学3区
文献类型:
--
作者:
Kalla, H;Yan, GX;Marinchak, R

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复发性心室颤动在一名29岁的越南男子中被观察到,他没有表现出结构性心脏病。患者心电图显示下导联明显的J (Osborn)波和ST段升高,与低体温、血清电解质紊乱、心肌缺血无关,J波振幅和ST段升高也有速率依赖性变化。植入植入式心律转复除颤器(ICD)。胺碘酮辅助治疗可降低J波振幅,预防心室颤动和ICD冲击。下导联J波突出、ST段抬高可作为诊断有不明原因晕厥病史的高危人群的重要诊断标志,ICD植入加胺碘酮是治疗的首选。
Recurrent ventricular fibrillation was observed in a 29-year-old Vietnamese man who did not exhibit structural heart disease. The patient's ECG showed prominent J (Osborn) waves and ST segment elevation in the inferior leads that were not associated with hypothermia, serum electrolyte disturbance, or myocardial ischemia, Rate-dependent change in the amplitude of J waves and ST segment elevation also were observed. An implantable cardioverter defibrillator (ICD) was implanted. Adjunctive treatment with amiodarone reduced J wave amplitude, preventing ventricular fibrillation and ICD shocks. Prominent J waves and ST segment elevation in the inferior leads may serve as an important diagnostic sign to detect high-risk individuals with a history of unexplained syncope, ICD implantation plus amiodarone is the treatment of choice.