Optimizing MRI contrast with B1 pulses using optimal control theory
Optimizing MRI contrast with B1 pulses using optimal control theory
复制标题
使用最优控制理论优化 B1 脉冲的 MRI 对比度
DOI：
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发表时间：
2016
期刊：
影响因子：
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通讯作者：
D. Sugny
中科院分区：
文献类型：
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作者：
E. V. Reeth;Helene Rafiney;Michael Tesch;S. Glaser;D. Sugny
MRI可实现的各种对比使其成为高度灵活和有价值的诊断工具。对比结果来自于松弛时间的差异，这是每个组织的固有特性。利用最优控制理论，可以通过施加激励脉冲使磁化强度处于用户定义的目标状态来控制所获得的对比度。仿真结果说明了采用最优对比度脉冲的可行性和灵活性。本文还研究了该方法对实验变参数如场不均匀性的鲁棒性。最后，在小动物MRI上进行了体外对比实验，结果与模拟结果吻合较好。
The variety of achievable contrasts by MRI makes it a highly flexible and valuable diagnostic tool. Contrast results from relaxation time differences, which are intrinsic properties of each tissue. Using optimal control theory, one can control the obtained contrast by applying excitation pulses that bring the magnetization in a user-defined target state. Simulation results are presented to illustrate the feasibility and the flexibility of using optimal contrast pulses. The robustness to experimental variable parameters such as field inhomogeneities is also studied. Finally, an in-vitro contrast experiment is performed on a small-animal MRI showing a reasonable match with the simulation results.
影响因子：
2.2
作者：
de Fouquieres, P.;Schirmer, S. G.;Kuprov, Ilya
通讯作者：
Kuprov, Ilya