Synthesis of the C1-C17 segment of phorboxazole B.
Synthesis of the C1-C17 segment of phorboxazole B.
复制标题
佛波唑 B 的 C1-C17 片段的合成。
DOI：
10.1021/ol0488800
复制
发表时间：
2004
期刊：
影响因子：
5.2
通讯作者：
Burke,StevenD
中科院分区：
文献类型：
--
作者：
Lucas,BrianS;Luther,LauraM;Burke,StevenD
The C1−C17 bis-oxane subunit22of phorboxazole B is efficiently synthesized by exploiting differential reactivities between similar substituents on the hydropyran rings in4. Selective dihydroxylation of the equatorial vinyl group, hydroboration of the axial vinyl group, and intramolecular Mitsunobu lactonization serve to fully differentiate the similar hydropyrans.
