Glaucoma and quality of life -: The Salisbury Eye Evaluation
Glaucoma and quality of life -: The Salisbury Eye Evaluation
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DOI：
10.1016/j.ophtha.2007.04.050
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发表时间：
2008-02-01
期刊：
影响因子：
13.7
通讯作者：
Friedman, David S.
中科院分区：
文献类型：
--
作者：
Freeman, Ellen E.;Munoz, Beatriz;Friedman, David S.
目的。在一项基于人群的研究中，研究青光眼状态或青光眼影响的视功能测量是否与自我报告的视力密集型任务困难相关。设计：横断面研究。参与者：参加第四轮索尔兹伯里眼科评估研究的一千一百六十人，他们的视力没有因青光眼以外的主要原因而低于20/40。方法：通过视神经头外观、视野（VF）测试、角镜检查和医生意见评估青光眼。使用日常视觉活动量表（ADVS）评估视觉相关的生活质量，其得分分为以下三类：视觉任务的最低难度，部分难度和最大难度。通过问卷调查和临床检查收集混杂因素的数据。采用多项逻辑回归对人口统计学和健康因素进行调整。主要观察指标：报告的ADVS困难程度。结果：双侧青光眼患者比无青光眼患者更有可能报告ADVS最困难（优势比[OR]， 3.25； 95%可信区间[CI]， 1.56-6.76），而单侧青光眼患者报告最困难的可能性较小（OR, 1.05； 95%可信区间[CI]， 0.38-2.91）。在调整了视力和对比敏感度后，较差的双眼VF评分与ADVS最困难的几率增加相关（OR, 1.48; 95% CI, 1.29-1.85）。结论：双侧青光眼患者比无青光眼患者在ADVS上更困难。这一发现，与双侧青光眼患者活动能力下降的研究结果相结合，表明青光眼影响了各种视觉任务的困难报告。
Purpose. To examine whether glaucoma status or measures of visual function affected by glaucoma are associated with self-reported difficulty with vision-intensive tasks in a population-based study.Design: Cross-sectional study.Participants: One thousand one hundred sixty individuals who participated in the fourth round of the Salisbury Eye Evaluation study and who did not have visual acuity worse than 20/40 due to a primary cause other than glaucoma.Methods: Glaucoma was assessed using optic nerve head appearance, visual field (VF) testing, gonioscopy, and physician opinion. Vision-related quality of life was assessed using the Activities of Daily Vision Scale (ADVS), whose scores were trichotomized into the following categories: the least difficulty with visual tasks, some difficulty, and the most difficulty. Data on confounders were collected by questionnaire and clinical examination. Multinomial logistic regression was used to adjust for demographic and health factors.Main Outcome Measure: Reported difficulty on the ADVS.Results: Individuals with bilateral glaucoma were more likely to report the most difficulty on the ADVS than those without glaucoma (odds ratio [OR], 3.25; 95% confidence interval [CI], 1.56-6.76), whereas those with unilateral glaucoma were not more likely to report the most difficulty (OR, 1.05; 95% CI, 0.38-2.91). Worse binocular VF scores were associated with increased odds of the most difficulty on the ADVS after adjusting for acuity and contrast sensitivity (OR, 1.48; 95% CI, 1.29-1.85).Conclusions: Individuals with bilateral glaucoma reported more difficulty on the ADVS than those without glaucoma. This finding, in conjunction with findings demonstrating decreased mobility in patients with bilateral glaucoma, points to the fact that glaucoma affects the report of difficulty with a variety of visual tasks.