Applications of Carbon Nanotubes in Bone Regenerative Medicine
Applications of Carbon Nanotubes in Bone Regenerative Medicine
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DOI：
10.3390/nano10040659
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发表时间：
2020-04
期刊：
影响因子：
5.3
通讯作者：
Manabu Tanaka;Kaoru Aoki;H. Haniu;Takayuki Kamanaka;T. Takizawa;Atsushi Sobajima;Kazushige Yoshida;M. Okamoto;Hiroyuki Kato;N. Saito
中科院分区：
文献类型：
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作者：
Manabu Tanaka;Kaoru Aoki;H. Haniu;Takayuki Kamanaka;T. Takizawa;Atsushi Sobajima;Kazushige Yoshida;M. Okamoto;Hiroyuki Kato;N. Saito
支架对骨再生至关重要，因为它们能够维持生长因子的持续释放，并提供形成新骨的细胞进入和增殖的地方。近年来，各种材料制成的支架得到了开发和评价。功能有效的支架需要优异的细胞亲和性、化学性能、机械性能和安全性。碳纳米管（Carbon nanotubes, CNTs）是一种直径为纳米级的纤维状纳米颗粒，具有优异的强度和化学稳定性。在工业领域，它们被用作填料来改善材料的性能。由于其优异的物理化学性质，碳纳米管作为生物材料的临床应用前景备受关注。本文综述了近年来碳纳米管支架在骨再生方面的研究成果，介绍了碳纳米管支架在骨再生方面的应用前景，并对碳纳米管支架的潜力进行了展望。
Scaffolds are essential for bone regeneration due to their ability to maintain a sustained release of growth factors and to provide a place where cells that form new bone can enter and proliferate. In recent years, scaffolds made of various materials have been developed and evaluated. Functionally effective scaffolds require excellent cell affinity, chemical properties, mechanical properties, and safety. Carbon nanotubes (CNTs) are fibrous nanoparticles with a nano-size diameter and have excellent strength and chemical stability. In the industrial field, they are used as fillers to improve the performance of materials. Because of their excellent physicochemical properties, CNTs are studied for their promising clinical applications as biomaterials. In this review article, we focused on the results of our research on CNT scaffolds for bone regeneration, introduced the promising properties of scaffolds for bone regeneration, and described the potential of CNT scaffolds.