Prevalence and Determinants of Herpes Simplex Virus Type 2 (HSV-2)/Syphilis Co-Infection and HSV-2 Mono-Infection among Human Immunodeficiency Virus Positive Men Who Have Sex with Men: a Cross-Sectional Study in Northeast China
Prevalence and Determinants of Herpes Simplex Virus Type 2 (HSV-2)/Syphilis Co-Infection and HSV-2 Mono-Infection among Human Immunodeficiency Virus Positive Men Who Have Sex with Men: a Cross-Sectional Study in Northeast China
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DOI：
10.7883/yoken.jjid.2016.177
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发表时间：
2017-05-01
影响因子：
2.2
通讯作者：
Shang, Hong
中科院分区：
文献类型：
--
作者：
Hu, Qing-hai;Xu, Jun-jie;Shang, Hong
本研究评估了中国人类免疫缺陷病毒（HIV）阳性男男性行为者（MSM）中 2 型单纯疱疹病毒（HSV2）/梅毒混合感染和 HSV-2 单一感染的流行率和决定因素。 2009年2月至2014年10月，对沉阳市545名HIV阳性MSM进行了横断面研究。参与者接受了体格检查以及HSV-2和梅毒血清学检测。使用多项 Logistic 回归来确定与 HSV-2/梅毒混合感染和 HSV-2 单一感染相关的危险因素。 HSV-2单一感染、梅毒单一感染和HSV-2/梅毒双重感染（95%置信区间）的患病率分别为48.6%（44.4-52.8%）、34.3%（30.3-38.3%）和22.9%（19.4-26.5%）。在控制HSV-2/梅毒血清阳性病例后，回归分析显示HSV-2/梅毒合并感染的相关因素包括年龄（25-50岁 vs. 50岁 vs. 50岁）。
This study assessed the prevalence and determinants of herpes simplex virus type 2 (HSV2)/syphilis co-infection and HSV-2 mono-infection in human immunodeficiency virus (HIV)-positive men who have sex with men (MSM) in China. A cross-sectional study was conducted of 545 HIV -positive MSM in Shenyang between February 2009 and October 2014. Participants underwent physical examinations and serological tests for HSV-2 and syphilis. A multinomial logistic regression was used to identify the risk factors associated with HSV-2/syphilis co-infection and HSV-2 mono-infection. The prevalence of HSV-2 mono-infection, syphilis mono-infection, and HSV-2/syphilis co-infection (95% confidence interval) was 48.6% (44.4-52.8%), 34.3% (30.3-38.3%), and 22.9% (19.4-26.5%), respectively. After controlling within HSV-2/syphilis-seropositive cases, regression analysis revealed that the related factors for HSV-2/syphilis co-infection included age (25-50 vs. 50 vs.