Characteristics of a multichannel electrooptical detection system and its application to the analysis of large molecules by fast atom bombardment mass spectrometry
Characteristics of a multichannel electrooptical detection system and its application to the analysis of large molecules by fast atom bombardment mass spectrometry
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多通道光电检测系统的特点及其在快原子轰击质谱分析大分子中的应用
DOI：
10.1021/ac00142a021
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发表时间：
1987
影响因子：
7.4
通讯作者：
S. Evans
中科院分区：
文献类型：
--
作者：
J. Cottrell;S. Evans
在许多应用中，扇形质谱计的灵敏度可以用多通道检测系统代替传统的单通道检测器而大大提高。本文研究了Kratos MS 50RF质谱仪光电“阵列”探测器的灵敏度、分辨率和动态范围特性。用快原子轰击电离法分析大分子时，检测限一般可降低100倍。质量范围为4%，可以同时检测到超过5000 fwhm的质量分辨率。单次曝光的动态范围约为1000，但可以通过在不同的积分时间进行进一步曝光来增加。
In many applications, the sensitivity of a sector mass spectrometer may be Increased dramatically by using a multichannel detection system In place of the conventional sin-gle-channel detector. In this work, the sensitivity, resolution, and dynamic range characteristics of an electrooptical “array” detector fittedto a Kratos MS50RF mass spectrometer have been Investigated. For the analysis of large mole-cules using fast atom bombardment Ionization, detection limits were typically reduced by a factor of100. A mass range of 4% can be detected simultaneously at a mass resolution In excess of 5000 fwhm. Dynamic range for a single exposure Is approximately 1000 but may be Increased by taking further exposures at different Integration times.