Evaluation of highly accelerated wave controlled aliasing in parallel imaging (Wave-CAIPI) susceptibility-weighted imaging in the non-sedated pediatric setting: a pilot study.
Evaluation of highly accelerated wave controlled aliasing in parallel imaging (Wave-CAIPI) susceptibility-weighted imaging in the non-sedated pediatric setting: a pilot study.
复制标题
非镇静儿科环境中并行成像 (Wave-CAIPI) 磁敏加权成像中高度加速波控制混叠的评估：一项试点研究。
DOI：
10.1007/s00247-021-05273-8
复制
发表时间：
2022
影响因子：
2.3
通讯作者：
Caruso,PaulJ
中科院分区：
文献类型：
--
作者：
Conklin,John;Tabari,Azadeh;Longo,MariaGabrielaFigueiro;Cobos,CamiloJaimes;Setsompop,Kawin;Cauley,StephenF;Kirsch,JohnE;Huang,SusieYi;Rapalino,Otto;Gee,MichaelS;Caruso,PaulJ
敏感性加权成像（SWI）对颅内出血和矿化病变高度敏感，但扫描时间较长。并行成像中的波控混叠（Wave- caipi）可以实现更大的加速因子，并可能促进SWI的更广泛应用，特别是在运动倾向人群中。目的比较非镇静儿科门诊环境中高加速Wave-CAIPI SWI与标准SWI在以下变量方面的差异：估计扫描时间、图像噪声、伪影、正常解剖可视化和病理可视化。材料与方法28名儿童（11名女孩，17名男孩，平均年龄±标准差[SD] = 128.3±62个月）接受了3-tesla (T)脑MRI，包括标准三维（3-D） SWI序列，然后对每个受试者进行高加速波caipi SWI序列。我们使用预定义的5分制对所有研究进行评分，并使用Wilcoxon符号秩检验来评估序列之间每个变量的差异。结果使用32通道和20通道线圈时，wave - caipi SWI分别减少了78%和67%的估计扫描时间，对应的估计扫描时间分别减少了3.5分钟和3分钟。所有28例患儿均在未麻醉的情况下进行影像学检查。读者间的一致性从一般到充分不等（病理学评价的k=0.67，解剖对比的k= 0.55，中心噪声的k= 0.3，伪影的k= 0.71）。SWI波对中央脑的图像噪声评分较高（P<0.01），而外周脑的图像噪声评分较低。标准SWI序列与波浪SWI序列在正常解剖结构显示和病理显示方面无显著差异（P=0.77和P=0.79）。结论：高加速的Wave-CAIPI SWI可以提供与标准SWI相似的图像质量，根据所使用的射频线圈的不同，估计扫描时间减少3-3.5分钟，运动伪影更少，但代价是中枢大脑的噪音轻微但明显增加。
BackgroundSusceptibility-weighted imaging (SWI) is highly sensitive for intracranial hemorrhagic and mineralized lesions but is associated with long scan times. Wave controlled aliasing in parallel imaging (Wave-CAIPI) enables greater acceleration factors and might facilitate broader application of SWI, especially in motion-prone populations.ObjectiveTo compare highly accelerated Wave-CAIPI SWI to standard SWI in the non-sedated pediatric outpatient setting, with respect to the following variables: estimated scan time, image noise, artifacts, visualization of normal anatomy and visualization of pathology.Materials and methodsTwenty-eight children (11 girls, 17 boys; mean age ± standard deviation [SD] = 128.3±62 months) underwent 3-tesla (T) brain MRI, including standard three-dimensional (3-D) SWI sequence followed by a highly accelerated Wave-CAIPI SWI sequence for each subject. We rated all studies using a predefined 5-point scale and used the Wilcoxon signed rank test to assess the difference for each variable between sequences.ResultsWave-CAIPI SWI provided a 78% and 67% reduction in estimated scan time using the 32- and 20-channel coils, respectively, corresponding to estimated scan time reductions of 3.5 min and 3 min, respectively. All 28 children were imaged without anesthesia. Inter-reader agreement ranged from fair to substantial (k=0.67 for evaluation of pathology, 0.55 for anatomical contrast, 0.3 for central noise, and 0.71 for artifacts). Image noise was rated higher in the central brain with wave SWI (P<0.01), but not in the peripheral brain. There was no significant difference in the visualization of normal anatomical structures and visualization of pathology between the standard and wave SWI sequences (P=0.77 andP=0.79, respectively).ConclusionHighly accelerated Wave-CAIPI SWI of the brain can provide similar image quality to standard SWI, with estimated scan time reduction of 3–3.5 min depending on the radiofrequency coil used, with fewer motion artifacts, at a cost of mild but perceptibly increased noise in the central brain.