Foot pulse oximeter perfusion index correlates with calf muscle perfusion measured by near-infrared spectroscopy in healthy neonates.
Foot pulse oximeter perfusion index correlates with calf muscle perfusion measured by near-infrared spectroscopy in healthy neonates.
复制标题
DOI：
10.1038/sj.jp.7211328
复制
发表时间：
2005-06-01
期刊：
影响因子：
--
通讯作者：
Chiandetti, Lino
中科院分区：
文献类型：
--
作者：
Zaramella, Patrizia;Freato, Federica;Chiandetti, Lino
目的：在危重新生儿中，外周灌注和氧合评估可提供循环休克期间重要器官循环衰竭的间接信息。脉搏血氧饱和度的发展，最近有可能计算灌注指数（PI），从吸收光的脉动和非脉动信号之间的比率。本研究的主要目的是：（1）研究足部PI;以及（2）评估通过脉搏血氧测定法连续获得的足部PI与多个变量（即，血流量（BF）、氧输送（DO（2））、氧消耗（VO（2））和氧提取分数（FOE））之间的关系，用近红外光谱法（NIRS）间接测定43例健康足月新生儿的小牛（体重3474.6 +/- 466.9 g;胎龄39.1 +/- 1.4周）。研究设计：通过NIRS对短期静脉和动脉闭塞操作评估小牛BF、DO（2）和VO（2）。PI测量对侧foot.RESULTS：脚PI为1.26 +/- 0.39。足PI与双小腿BF呈正相关（r = 0.32，p = 0.03）和DO（2）（r = 0.32，p = 0.03），但未发现足部PI与小腿FOE以及足部PI与VO（2）之间存在相关性。在新生儿重症监护室，通过脉搏血氧仪连续测量足部PI在临床上似乎比小腿BF和/或VO的点测量更适用于外周灌注监测（2）间接NIRS
OBJECTIVE: In critically ill neonates, peripheral perfusion and oxygenation assessment may provide indirect information on the circulatory failure of vital organs during circulatory shock. The development of pulse oximetry has recently made it possible to calculate the perfusion index (PI), obtained from the ratio between the pulsatile and nonpulsatile signals of absorbed light. The main goals of this study were: (1) to study foot PI; and (2) to evaluate the relationship between foot PI, obtained continuously by pulse oximetry, and a number of variables, i.e. blood flow (BF), oxygen delivery (DO(2)), oxygen consumption (VO(2)), and fractional oxygen extraction (FOE), measured indirectly by near-infrared spectroscopy (NIRS) on the calf in 43 healthy term neonates (weight 3474.6 +/- 466.9 g; gestational age 39.1 +/- 1.4 weeks).STUDY DESIGN: Calf BF, DO(2) and VO(2) were assessed by NIRS on short-lived venous and arterial occlusion maneuvers. PI was measured on the contralateral foot.RESULTS: Foot PI was 1.26 +/- 0.39. There was a positive correlation between foot PI and both calf BF (r = 0.32, p = 0.03) and DO(2) (r = 0.32, p = 0.03), but no correlation was found between foot PI and calf FOE and between foot PI and VO(2).CONCLUSIONS: In the neonatal intensive care unit, continuously measuring foot PI by pulse oximetry seems clinically more feasible for peripheral perfusion monitoring than spot measurements of the calf BF and/or VO(2) by indirect NIRS.