Growth of adolescents who were born at extremely low birth weight without major disability

Growth of adolescents who were born at extremely low birth weight without major disability
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DOI:
10.1067/mpd.2000.104291
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发表时间:
2000-05-01
影响因子:
5.1
通讯作者:
Nelson, KG
Nelson, KG
中科院分区:
医学2区
文献类型:
--
作者:
Peralta-Carcelen, M;Jackson, DS;Nelson, KG

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目的:比较极低出生体重(ELBW,小于或等于 1000 克)出生的青少年和正常出生体重(NBW,大于或等于 2500 克)出生的青少年的生长情况。 设计/方法:横断面设计。 53 名没有严重神经发育障碍的 ELBW 和 53 名 NBW 青少年在性别、种族、年龄和社会经济地位上进行了匹配。评估了人体测量学(z 分数)、骨龄、身体成分(月球 DPX-L 密度测量)和性成熟度。 ELBW 青少年被分为小于胎龄 (SGA) 或小于胎龄 (NSGA)。 结果:受试者中 58.5% 为女性,43.4% 为黑人,56.6% 为白人。 ELBW 受试者的平均出生体重为 849 克,新受试者的平均出生体重为 3355 克。平均年龄为14.85岁。平均而言,ELBW 青少年比 NEW 青少年矮 4.8 厘米,轻 9.1 公斤。 ELBW 青少年的身高 (P < .0001)、体重 (P < .0001) 和头围 (P < .0001) 的平均 x 得分低于新青少年。 ELBW/SGA 受试者的身高 (P < .0001) 和体重 (P = .001) 平均 x 分数低于 NEW 受试者。 ELBW/SGA 组的头围 = 分数低于 ELBW/NSGA 组或 NEW 组 (P = .003)。各组之间的性成熟度和相对身体成分相似。以 SD 单位测量的骨龄在 ELBW 组中更先进(0.86 vs. 0.42,P = 0.039)。 结论:与新青少年相比,没有出现重大神经发育障碍的 ELBW 青少年的生长测量值较低,但具有相似的性成熟和相对身体成分。
Objective: To compare growth between adolescents who were born at extremely low birth weight (ELBW, less than or equal to 1000 g) and adolescents who were born at normal birth weight (NBW, greater than or equal to 2500 g).Design/Methods: Cross-sectional design. Fifty-three ELBW and 53 NBW adolescents without a major neurodevelopmental disability were matched by sex, race, age, and socioeconomic status. Anthropometrics (z scores), bone age, body composition (Lunar DPX-L densitometry), and sexual maturity were assessed. ELBW adolescents were classified as being born small for gestational age (SGA) or not (NSGA).Results: Subjects were 58.5% female, 43.4% black, and 56.6% white. The mean birth weight for ELBW subjects was 849 g and 3355 g for NEW subjects. The mean age was 14.85 years. On average, ELBW adolescents were 4.8 cm shorter and 9.1 kg lighter than NEW adolescents. ELBW adolescents had lower mean x scores for height (P < .0001), weight (P < .0001), and head circumference(P < .0001) than NEW adolescents. ELBW/SGA subjects had lower mean,x scores for height (P < .0001) and weight (P = .001) than NEW subjects. Head circumference = scores were lower for the ELBW/SGA group than the ELBW/NSGA group or the NEW group (P = .003). Sexual maturity and relative body composition were similar between groups. Bone age, measured in SD units, was more advanced in the ELBW group (0.86 vs. 0.42, P = .039).Conclusions: ELBW adolescents who survive without a major neurodevelopmental disability attain lower growth measurements compared with NEW adolescents but have similar sexual maturation and relative body composition.