Abnormal molecular response to Takayasu arteritis causing extensive large-vessel calcification.
Abnormal molecular response to Takayasu arteritis causing extensive large-vessel calcification.
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DOI：
10.1016/j.jvscit.2016.05.004
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发表时间：
2016-12
影响因子：
--
通讯作者：
Starnes BW
中科院分区：
文献类型：
--
作者：
Garland BT;Boehm M;Grayson PC;Hilaire CS;Brofferio A;Starnes BW
多发性大动脉炎是一种大血管炎，经常导致无脉由于纤维化狭窄。虽然轻微钙化有时见于多发性大动脉炎，但很少引起狭窄。导致灌注不良的广泛钙化是非常罕见的，并且被归因于慢性炎症状态下的钙运输障碍。我们报告一个不寻常的情况下，迅速进行性和广泛的主动脉钙化的设置大动脉炎。
Takayasu arteritis is a large-vessel vasculitis that often results in pulselessness due to fibrotic stenoses. Whereas minor calcification is sometimes seen with Takayasu arteritis, it rarely causes stenosis. Extensive calcification resulting in malperfusion is exceedingly rare and has been attributed to disorders in calcium trafficking in a chronic inflammatory state. We report an unusual case of rapidly progressive and extensive aortic calcification in the setting of Takayasu arteritis.