Transabdominal Measurement of Placental Oxygenation by Near-infrared Spectroscopy
Transabdominal Measurement of Placental Oxygenation by Near-infrared Spectroscopy
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DOI：
10.1055/s-0029-1234038
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发表时间：
2010-01-01
影响因子：
2
通讯作者：
Kanayama, Naohiro
中科院分区：
文献类型：
--
作者：
Kakogawa, Jun;Sumimoto, Kazuhiro;Kanayama, Naohiro
我们评估了近红外光谱定量测量胎盘组织氧合对孕妇子宫胎盘功能无创估计的临床实用性。我们进行了一项前瞻性观察性临床研究。无并发症的妇女（n = 15）和妊娠高血压综合征（PIH; n = 6）的妇女入组。使用NIRO-300（日本滨松市滨松光子学公司（Hamamatsu Photonics，Hamamatsu City，Japan））记录胎盘组织氧合指数（TOI）的测量。无并发症孕妇的TOI平均值为72.36 ± 5.36%，妊高征孕妇的TOI平均值为80.28 ± 2.78%。妊高征孕妇TOI均值高于无并发症孕妇。TOI与妊高征发病时的胎龄、妊高征的类型或高血压的严重程度无差异。孕妇的TOI较高，提示胎盘功能下降。通过近红外光谱定量测量来监测TOI可能具有很高的临床应用潜力，特别是在产前管理中。
We evaluated the clinical usefulness of near-infrared spectroscopic quantitative measurement of placental tissue oxygenation for noninvasive estimation of uteroplacental function in pregnant women. We performed a prospective observational clinical study. Women without complications (n = 15) and women with pregnancy-induced hypertension (PIH; n = 6) were enrolled. Measurements of placental tissue oxygenation index (TOI) using NIRO-300 (Hamamatsu Photonics, Hamamatsu City, Japan) were recorded. The mean TOI in women without complications was 72.36 +/- 5.36% and 80.28 +/- 2.78% in pregnant women with PIH. The mean TOI in pregnant women with PIH was higher than that of pregnant women without complications. There were no differences in the TOI in relation to gestational age at onset of PIH, forms of PIH, or severity of hypertension. Higher TOIs in pregnant women suggest the reduced ability of the placental function. Monitoring the TOI by near-infrared spectroscopic quantitative measurement may have a high potential for clinical application, particularly in prenatal management.