Kottamides A-D:: Novel bioactive imidazolone-containing alkaloids from the New Zealand ascidian Pycnoclavella kottae
Kottamides A-D:: Novel bioactive imidazolone-containing alkaloids from the New Zealand ascidian Pycnoclavella kottae
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DOI：
10.1021/jo0201427
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发表时间：
2002-07-26
影响因子：
3.6
通讯作者：
Copp, BR
中科院分区：
文献类型：
--
作者：
Appleton, DR;Page, MJ;Copp, BR
Kottamides A-D (1-4), novel 2,2,5-trisubstituted imidazolone-containing alkaloids, were isolated from the New Zealand endemic ascidian Pycnoclavella kottae and structurally characterized using N-15 natural abundance 2-D NMR in addition to standard spectroscopic methods. The kottamides exhibited anti-inflammatory and anti-metabolic activity as well as cytotoxicity toward tumor cell lines.
