Neuronal activity related to anticipated and elapsed time in macaque supplementary eye field
Neuronal activity related to anticipated and elapsed time in macaque supplementary eye field
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DOI：
10.1007/s00221-007-1234-3
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发表时间：
2008-02-01
影响因子：
2
通讯作者：
Kitazawa, Shigeru
中科院分区：
文献类型：
--
作者：
Ohmae, Shogo;Lu, Xiaofeng;Kitazawa, Shigeru
在我们的日常生活中，感知预期时间和已经过的时间是必不可少的。大脑的几个区域，包括顶叶皮层、前额叶皮层、基底神经节和橄榄小脑系统，已知与这种时间处理有关。我们现在描述了辅助视野（SEF）中的一些细胞，它们具有随延迟期长度而变化的相位、延迟活动和延迟后活动调制。这种变化以两种方式发生。首先，细胞变得活跃的延迟时间更短（GO信号出现得更早）。我们称这些细胞为“短延迟细胞”。其次，细胞变得活跃的延迟时间较长（GO信号出现较晚）。我们称这些细胞为“长延迟细胞”。然而，这种神经元活动的变化与反应时间无关。这些结果表明，延迟相关的活动可能反映了延迟跳眼运动的预期时间和经过的时间。
It is essential to sense anticipated and elapsed time in our daily life. Several areas of the brain including parietal cortex, prefrontal cortex, basal ganglia and olivo-cerebellar system are known to be related to this temporal processing. We now describe a number of cells in the supplementary eye field (SEF) with phasic, delay activity and postdelay activity modulation that varied with the length of the delay period. This variation occurred in two manners. First, cells became active with the shorter delay periods (GO signal presented earlier). We call these cells "short-delay cells". Second, cells became active with the longer delay periods (GO signal presented later). We call these cells "long-delay cells". However, such changed neuronal activity did not correlate with reaction time. These results suggest that the delay-dependent activity may reflect anticipated and elapsed time during performance of a delayed saccadic eye movement.