Depression of corticospinal cells by various purines and pyrimidines.
Depression of corticospinal cells by various purines and pyrimidines.
复制标题
各种嘌呤和嘧啶抑制皮质脊髓细胞。
DOI:
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发表时间:
1974
影响因子:
2.1
通讯作者:
J. Limacher
中科院分区:
文献类型:
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作者:
J. Phillis;G. Kostopoulos;J. Limacher
Microiontophoretically applied adenine nucleotides depressed the firing of corticospinal and other unidentified cerebral cortical neurones. Adenosine 3′,5′-cyclic monophosphate was less potent than the other adenine nucleotides. Guanine nucleotides shared this depressant activity, although they were less potent. Pyrimidine nucleotides and xanthine derivatives were largely devoid of depressant activity. Adenosine triphosphate had an additional excitant action on some neurones, but this effect was not observed with corticospinal cells.