Organ Doses from Chest Radiographs in Tuberculosis Patients in Canada and Their Uncertainties in Periods from 1930 to 1969.
Organ Doses from Chest Radiographs in Tuberculosis Patients in Canada and Their Uncertainties in Periods from 1930 to 1969.
复制标题
1930 年至 1969 年间加拿大结核病患者胸部 X 光片的器官剂量及其不确定性。
DOI：
10.1097/hp.0000000000001171
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发表时间：
2020
期刊：
影响因子：
2.2
通讯作者：
Zablotska,LydiaB
中科院分区：
文献类型：
--
作者：
Kocher,DavidC;Apostoaei,AIulian;Thomas,BrianA;Borrego,David;Lee,Choonsik;Zablotska,LydiaB
本文介绍了一项研究，以估计吸收剂量的各种器官，从胶片为基础的胸部X光照片及其不确定性，在1930年至1948年，1949年至1955年，1956年至1969年期间。估计的器官剂量将用于对加拿大结核病患者的癌症和其他疾病风险进行新的分析，这些患者在这些时期进行了胸部荧光镜和放射学检查。本文使用以下数据估计加拿大队列中1岁、5岁、10岁和15岁成人和儿童的单次胸片对肺、女性乳腺、活性骨髓和心脏的剂量及其不确定性：（1）管电压（kV）、总滤过（mm Al）、管电流滤过时间乘积（mA s）、和每个周期的管输出（mR [mA s]− 1）;（2）关于患者方向、从源到患者皮肤的距离和胶片尺寸的假设;（3）性别和年龄特异性器官剂量转换系数（皮肤入口处空气中的器官剂量）的新计算。在这三个时期内，每个器官的估计剂量变化在成人中不到20%，在年轻人中高达约30%。估计器官剂量的不确定性在成人中约为2至3倍，在较年轻的年龄中高达4倍，主要是由于管电压和管电流的不确定性-时间乘积。
This paper describes a study to estimate absorbed doses to various organs from film-based chest radiographs and their uncertainties in the periods 1930 to 1948, 1949 to 1955, and 1956 to 1969. Estimated organ doses will be used in new analyses of risks of cancer and other diseases in tuberculosis patients in Canada who had chest fluoroscopic and radiographic examinations in those periods. In this paper, doses to lungs, female breast, active bone marrow, and heart from a single chest radiograph in adults and children of ages 1, 5, 10, and 15 y in the Canadian cohort and their uncertainties are estimated using (1) data on the tube voltage (kV), total filtration (mm Al), tube-current exposure-time product (mA s), and tube output (mR [mA s]− 1) in each period;(2) assumptions about patient orientation, distance from the source to the skin of a patient, and film size; and (3) new calculations of sex-and age-specific organ dose conversion coefficients (organ doses per dose in air at skin entrance). Variations in estimated doses to each organ across the three periods are less than 20% in adults and up to about 30% at younger ages. Uncertainties in estimated organ doses are about a factor of 2 to 3 in adults and up to a factor of 4 at younger ages and are due mainly to uncertainties in the tube voltage and tube-current exposure-time product.