Inactivation of SARS-CoV-2 in Water by Chlorination.
Inactivation of SARS-CoV-2 in Water by Chlorination.
复制标题
通过氯化灭活水中的 SARS-CoV-2。
DOI：
10.1007/s12560-023-09559-y
复制
发表时间：
2023
影响因子：
3.4
通讯作者：
Gerba,CharlesP
中科院分区：
文献类型：
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作者：
Sherchan,Samendra;Ikner,LuisaA;Gerba,CharlesP
严重急性呼吸综合征冠状病毒-2 （SARS-CoV-2）存在于呼吸道分泌物和粪便中，有可能通过游泳池传播。众所周知，娱乐水上活动增加了呼吸道感染的风险，并且在游泳池中发现并引起了呼吸道病毒的爆发。然而，人们对美国游泳池典型水中SARS-CoV-2的氯灭活知之甚少。本研究通过氯化法观察了SARS-CoV-2分离株hCoV-19/USA-WA1/2020在水中的失活情况。所有实验均在BSL-3实验室室温下进行。结果表明，在2.05 mg/L游离氯接触30 s后，病毒的检出限降低了3.5 log(> 99.9%)，在2 min内，病毒的检出限降低了4.17 log（> 99.99%）。
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is present in both respiratory secretions and feces, creating its potential for transmission by swimming pools. Recreational water activity is known to be at increased risk of respiratory infections and respiratory viruses have caused been detected and have caused outbreaks in swimming pools. However, little is known regarding the chlorine inactivation of SARS-CoV-2 in water typical of swimming pools in the USA. In this study, the inactivation of SARS-CoV-2 Isolate hCoV-19/USA-WA1/2020 was observed in water by chlorination. All experiments were conducted within a BSL-3 laboratory at room temperature. Our results show that the virus was reduced by 3.5 log (> 99.9%) after 30 s of 2.05-mg/L free chlorine contact and greater than 4.17 log (limit of detection) (> 99.99%) within 2 min.