The Economic and Social Burden of the 2014 Ebola Outbreak in West Africa
The Economic and Social Burden of the 2014 Ebola Outbreak in West Africa
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DOI：
10.1093/infdis/jiy213
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发表时间：
2018-12-15
影响因子：
6.4
通讯作者：
Stevens, Warren
中科院分区：
文献类型：
--
作者：
Huber, Caroline;Finelli, Lyn;Stevens, Warren
2014年西非爆发的埃博拉病毒病（EVD）比以往所有埃博拉病毒病暴发的总和更具破坏性；然而，对其经济负担的许多估计没有包括其重大的社会成本。本研究旨在审查目前所有可用的估计数，确定这些估计数遗漏的社会组成部分，并得出2014年埃博拉病毒病暴发的综合成本。方法：我们对灰色报告（由非营利组织或非政府组织、政府或行业产生的报告）和已发表的文献进行了系统回顾，以确定当前对疫情负担的估计。根据本综述的发现，我们确定了6个关键领域，这些领域在以前的估计中缺失或被低估，并使用文献和外推法的估计计算了被低估的社会成本。结果目前对疫情造成的经济负担的估计范围为国内生产总值损失28亿至326亿美元。我们估计2014年埃博拉病毒病暴发造成的综合经济和社会负担为531.9亿美元（2014年美元）。其中最重要的188亿美元是由非埃博拉原因造成的死亡。结论：对2014年埃博拉病毒病疫情负担的更全面了解凸显了能够减轻或降低未来疫情严重程度的干预措施的价值。
Background The 2014 Ebola virus disease (EVD) outbreak in West Africa was more devastating than all previous EVD outbreaks combined; however, many estimates of its economic burden did not capture its significant social costs. This study aimed to review all currently available estimates, identify social components missed by these estimates, and generate a comprehensive cost of the 2014 EVD outbreak.Methods We conducted a systematic review of the grey (reports produced by nonprofit or nongovernmental organizations, government, or industry) and published literature to identify current estimates of the burden of the outbreak. Based on the findings of this review, we identified 6 key areas absent or underestimated from previous estimates and calculated the underestimated social costs using estimates from the literature and extrapolation.Results Current estimates of the economic burden of the outbreak range from $2.8 to $32.6 billion in lost gross domestic product. We estimated the comprehensive economic and social burden from the 2014 EVD outbreak to be $53.19 billion (2014 USD). The most significant component, $18.8 billion, was deaths from non-Ebola causes.Conclusions A more complete understanding of the burden of the 2014 EVD outbreak underscores the value of interventions that can mitigate or reduce the severity of future outbreaks.