Factors associated with discrepancies between self-reports on cigarette smoking and measured serum cotinine levels among persons aged 17 years or older - Third National Health and Nutrition Examination Survey, 1988-1994
Factors associated with discrepancies between self-reports on cigarette smoking and measured serum cotinine levels among persons aged 17 years or older - Third National Health and Nutrition Examination Survey, 1988-1994
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DOI：
10.1093/aje/153.8.807
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发表时间：
2001-04-15
影响因子：
5
通讯作者：
Mowery, PD
中科院分区：
文献类型：
--
作者：
Caraballo, RS;Giovino, GA;Mowery, PD
在一次访谈中报告的吸烟状况与尼古丁生物标记物--血清可替宁的测量水平之间的差异，在一个年龄大于或等于17岁的美国人口的代表性样本中进行了调查(N=15,357)。数据收集自第三次全国健康和营养检查调查(1988-1994年)的参与者。在自我报告的吸烟者中，7.5%(95%可信区间：6.3，8.7)的血清可替宁水平低于或等于15.0 ng/ml，这是识别非吸烟者的选定分界点。年龄(p<；0.01)、种族/民族(p<；0.01)和平均每天吸烟次数(p<；0.01)与这些不一致的结果有关。在自我报告的非吸烟者中，1.4%(95%可信区间：1.1，1.7)的血清可替宁水平大于15.0 ng/ml，这是确定吸烟者的选定截止点。种族/民族(p<；0.01)、教育程度(p<；0.01)、在家中吸烟的家庭成员数量(p=0.03)以及之前家庭访谈中自我报告的吸烟状况(p<；0.01)与这些不一致的结果有关。吸烟模式的不同，包括尼古丁剂量的不同，可能解释了自我报告的吸烟者之间观察到的大部分差异，而关于吸烟状况的欺骗可能解释了自我报告的不吸烟者的大部分差异。这项研究提供了证据，证明在私人医疗环境中进行的基于人群的调查中，成年受访者自我报告的吸烟状况是准确的。
The discrepancy between cigarette smoking status reported during an interview and measured level of serum cotinine, a nicotine biomarker, was investigated in a representative sample of the US population aged greater than or equal to 17 years (N = 15,357). Data were collected from participants in the Third National Health and Nutrition Examination Survey (1988-1994). Among self-reported smokers, 7.5% (95% confidence interval: 6.3, 8.7) had a serum cotinine level less than or equal to 15.0 ng/ml, the selected cutoff point for identifying nonsmokers. Age (p < 0.01), race/ethnicity (p < 0.01), and average number of cigarettes smoked per day (p < 0.01) were associated with these discrepant findings. Among self-reported nonsmokers, 1.4% (95% confidence interval: 1.1, 1.7) had a serum cotinine level greater than 15.0 ng/ml, the selected cutoff point for identifying smokers. Race/ethnicity (p < 0.01), education (p < 0.01), number of household members who smoked in the home (p = 0.03), and self-reported smoking status from an earlier home interview (p < 0.01) were associated with these discrepant findings. Differences in smoking patterns, including the extent of nicotine dosing, may explain most of the discrepancy observed among self-reported smokers, whereas deception regarding smoking status may explain most of the discrepancy among self-reported nonsmokers. This study provides evidence that self-reported smoking status among adult respondents to a population-based survey conducted in a private medical setting is accurate.