Cardiorespiratory Fitness Is Associated With Cognitive Performance in Older But Not Younger Adults
Cardiorespiratory Fitness Is Associated With Cognitive Performance in Older But Not Younger Adults
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DOI：
10.1093/geronb/gbu167
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发表时间：
2016-05-01
影响因子：
6.2
通讯作者：
Verfaellie, Mieke
中科院分区：
文献类型：
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作者：
Hayes, Scott M.;Forman, Daniel E.;Verfaellie, Mieke
目的：衰老与执行功能和情景记忆的下降有关。在老年人（OA）中，呼吸适应性（CRF）与执行功能增强有关，但与情景记忆的关系尚不清楚。本研究的目的是探讨CRF和认知之间的关系，在年轻和OA和CRF是否减轻与年龄相关的认知decline.Methods：参与者完成了运动测试，以评估CRF（峰值VO2）和神经心理测试，以评估cognition.Results：在OA，峰值VO2是正相关的执行功能，以及准确性的实验面孔名称记忆任务和视觉情景记忆。在年轻人（YA）中，峰值VO2与认知之间的关系不明显。高适应OA执行功能的措施，以及YA。情景记忆的措施，YA表现优于高契合度OA，谁反过来表现优于低契合度OA.Conclusions：CRF与OA的执行功能和情景记忆呈正相关，并减弱与年龄相关的认知能力下降。我们提供了初步的年龄依赖性假说的支持，假设认知和CRF的关系可能是最容易观察到在一生中的显着神经认知发展。
Objectives: Aging is associated with declines in executive function and episodic memory. Cardiorespiratory fitness (CRF) has been associated with enhanced executive function in older adults (OA), but the relationship with episodic memory remains unclear. The purpose of the study was to examine the relationship between CRF and cognition in young and OA and whether CRF mitigates age-related cognitive decline.Methods: Participants completed exercise testing to evaluate CRF (peak VO2) and neuropsychological testing to assess cognition.Results: In OA, peak VO2 was positively related to executive function, as well as to accuracy on an experimental face-name memory task and visual episodic memory. In young adults (YA), a relationship between peak VO2 and cognition was not evident. High-fit OA performed as well as YA on executive function measures. On episodic memory measures, YA performed better than high-fit OA, who in turn performed better than low-fit OA.Conclusions: CRF is positively associated with executive function and episodic memory in OA and attenuates age-related cognitive decline. We provide preliminary support for the age-dependence hypothesis, which posits that cognition and CRF relationships may be most readily observed during lifetime periods of significant neurocognitive development.