Absence of age-related increase in central arterial stiffness in physically active women

Absence of age-related increase in central arterial stiffness in physically active women
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DOI:
10.1161/01.atv.18.1.127
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发表时间:
1998-01-01
影响因子:
8.7
通讯作者:
Seals, DR
Seals, DR
中科院分区:
医学1区
文献类型:
--
作者:
Tanaka, H;DeSouza, CA;Seals, DR

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动脉僵硬的增加被认为是随着年龄的增长心血管疾病发病率增加的原因。然而,关于衰老对女性中央和外周动脉僵硬的影响,人们知之甚少。此外,尚不清楚身体活动状况是否会影响女性与年龄相关的动脉僵硬增加。对53例健康女性,包括10例绝经前(S前)和18例绝经后(S后)久坐不动的女性,以及9例绝经前(PA前)和16例绝经后(PA后)体力活动女性进行了动脉脉搏波速度(PWV)和增强指数(AI)的测定。久坐不动的女性,动脉压无年龄差异,但动脉PWV和颈动脉A1(衡量中央动脉僵硬度的指标)较高(P
Increased arterial stiffness is thought to contribute to the increased incidence of cardiovascular disease with age. Little, however, is known about the influence of aging on central and peripheral arterial stiffness in females. Moreover, it is unknown whether physical activity status influences age-related increases in arterial stiffness in females. Arterial pulse wave velocity (PWV) and augmentation index (AI, applanation tonometry) were measured in 53 healthy females, including 10 premenopausal (Pre-S) and 18 postmenopausal (Post-S) sedentary women, and 9 premenopausal (Pre-PA) and 16 postmenopausal (Post-PA) physically active women. In the sedentary women, there were no age-related differences in arterial blood pressure, but aortic PWV and carotid Al (measures of central arterial stiffness) were higher (P