Alveolar echinococcosis of the liver in a six-year-old girl with acquired immunodeficiency syndrome
Alveolar echinococcosis of the liver in a six-year-old girl with acquired immunodeficiency syndrome
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DOI：
10.1016/s0022-3476(97)70364-0
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发表时间：
1997-02-01
影响因子：
5.1
通讯作者：
Gottstein, B
中科院分区：
文献类型：
--
作者：
Sailer, M;Soelder, B;Gottstein, B
一名患有获得性免疫缺陷综合征（艾滋病）的6岁女孩患有广泛的泡型棘球蚴病。通过对受影响肝脏组织标本进行针刺活检确诊。该病例的特点是患者年龄异常小，更确切地说，在确诊时或之后没有任何可检测到的寄生虫特异性体液和细胞免疫反应。因此，本病例表明，艾滋病导致的明显免疫缺陷可能极大地促进了该疾病的快速增殖和早期表现。对于患有儿童艾滋病且生活在多房棘球绦虫流行地区的患者，即使免疫诊断检测结果为阴性，肝内肿瘤样病变也应考虑泡型棘球蚴病。
A 6-year-old girl with acquired immunodeficiency syndrome (AIDS) had extensive alveolar echinococcosis. Diagnosis was proved by needle biopsy of a specimen from affected liver tissue. The case was characterized by the unusually young age of the patient and more specifically by the absence of any detectable parasite-specific humoral and cellular immune response at diagnosis or later. Thus the present case indicates that a marked immunodeficiency caused by AIDS may substantially contribute to the rapid proliferation and early manifestation of the disease. In patients with pediatric AIDS and living in areas endemic for Echinococcus multilocularis, alveolar echinococcosis should be considered in intrahepatic tumorlike lesions even if the result of immunodiagnostic testing is negative.