Wide-field absolute transverse blood flow velocity mapping in vessel centerline
Wide-field absolute transverse blood flow velocity mapping in vessel centerline
复制标题
血管中心线的宽视场绝对横向血流速度测绘
DOI：
10.1117/1.jbo.23.2.026008
复制
发表时间：
2018
影响因子：
3.5
通讯作者：
Zeng Yaguang
中科院分区：
文献类型：
--
作者：
Wu Nanshou;Wang Lei;Zhu Bifeng;Guan Caizhong;Wang Mingyi;Han Dingan;Tan Haishu;Zeng Yaguang
抽象的。提出了一种基于吸收强度涨落调制效应的血管中线宽视场绝对横向血流速度测量方法。利用红细胞和背景组织在低相干光照射下的光吸收能力的差异，实现了瞬时和平均广域光学血管成像。采用绝对模糊连接算法从平均宽视野光学血管成像中提取血管中心线。然后根据瞬时调制深度信号，通过互相关分析测量血管中心线上的绝对横向速度。建议的方法有望有助于疾病的治疗，如与贫血或血栓形成有关的疾病。
Abstract. We propose a wide-field absolute transverse blood flow velocity measurement method in vessel centerline based on absorption intensity fluctuation modulation effect. The difference between the light absorption capacities of red blood cells and background tissue under low-coherence illumination is utilized to realize the instantaneous and average wide-field optical angiography images. The absolute fuzzy connection algorithm is used for vessel centerline extraction from the average wide-field optical angiography. The absolute transverse velocity in the vessel centerline is then measured by a cross-correlation analysis according to instantaneous modulation depth signal. The proposed method promises to contribute to the treatment of diseases, such as those related to anemia or thrombosis.