Molecular Characterization, Expression Patterns, and Association Analysis with Carcass Traits of Porcine USF1 Gene
Molecular Characterization, Expression Patterns, and Association Analysis with Carcass Traits of Porcine USF1 Gene
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猪USF1基因的分子特征、表达模式及与胴体性状的关联分析
DOI:
10.1007/s12010-013-0280-5
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发表时间:
2013-05
影响因子:
3
通讯作者:
Mei, Shuqi
中科院分区:
文献类型:
--
作者:
Liu, Guisheng;Sun, Hua;Li, Lianghua;Mei, Shuqi
The upstream stimulatory factor 1 (USF1) is a transcription factor controlling expression of several genes involved in lipid and glucose homeostasis. In this study, two isoforms of the porcine USF1 gene were detected by reverse transcription polymerase chain reaction (RT-PCR), termed USF1 wild-type (wt) and USF1/CD, both of them contain a helix-loop-helix leucine zipper (HLH-LZ) conserved domain. Tissue distribution analysis showed that the two transcripts of porcine USF1 gene were ubiquitously expressed in all tested tissues, except for heart. Moreover, we found that a single nucleotide polymorphism (SNP, C/T) in intron 10 was significantly associated with ratio of lean to fat (P < 0.05), dress percentage (P < 0.05), average backfat thickness (P < 0.05), loin eye width (P < 0.05), lean meat percentage (P < 0.01), loin eye height (P < 0.01), and loin eye area (P < 0.01). This result suggests that porcine USF1 gene may be a candidate gene of meat production trait.
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影响因子:
6.5
作者:
Xiaoping Yang;L. Freeman;C. Knapper;M. Amar;A. Remaley;H. Brewer;S. Santamarina-Fojo
通讯作者:
Xiaoping Yang;L. Freeman;C. Knapper;M. Amar;A. Remaley;H. Brewer;S. Santamarina-Fojo
影响因子:
4.5
作者:
Komulainen K;Alanne M;Auro K;Kilpikari R;Pajukanta P;Saarela J;Ellonen P;Salminen K;Kulathinal S;Kuulasmaa K;Silander K;Salomaa V;Perola M;Peltonen L
通讯作者:
Peltonen L
影响因子:
14.9
作者:
SIRITO, M;LIN, Q;SAWADOGO, M
通讯作者:
SAWADOGO, M
影响因子:
5.8
作者:
Hoffstedt, J;Rydén, M;Arner, P
通讯作者:
Arner, P
影响因子:
3.3
作者:
S. Knott;L. Marklund;Chris S Haley;Kjell Andersson;William Davies;Hans Ellegren;M. Fredholm;
通讯作者:
S. Knott;L. Marklund;Chris S Haley;Kjell Andersson;William Davies;Hans Ellegren;M. Fredholm;