FATTY-ACID LEVELS IN THE BRAINS OF SCHIZOPHRENICS AND NORMAL CONTROLS
FATTY-ACID LEVELS IN THE BRAINS OF SCHIZOPHRENICS AND NORMAL CONTROLS
复制标题
DOI：
10.1016/0006-3223(91)90235-e
复制
发表时间：
1991-10-15
影响因子：
10.6
通讯作者：
GLEN, M
中科院分区：
文献类型：
--
作者：
HORROBIN, DF;MANKU, MS;GLEN, M
必需脂肪酸是大脑的重要组成部分。 有证据表明，血液中某些必需脂肪酸及其类二十烷酸衍生物的水平可能异常。 我们现在报道，精神分裂症患者的额叶皮层中磷脂酰乙醇胺的脂肪酸组成与正常人存在显着差异。 在小脑皮质中没有发现这些与正常情况的差异。
Essential fatty acids are important constituents of the brain. There is evidence that levels in blood of certain essential fatty acids and their eicosanoid derivatives may be abnormal. We now report that in the frontal cortex of schizophrenic patients there are significant differences from normal in the fatty acid composition of phosphatidylethanolamine. These differences from normal were not found in the cerebellar cortex.