Citrus fruits as a treasure trove of active natural metabolites that potentially provide benefits for human health.
Citrus fruits as a treasure trove of active natural metabolites that potentially provide benefits for human health.
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柑橘类水果是活性天然代谢物的宝库，可能为人类健康带来益处
DOI：
10.1186/s13065-015-0145-9
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发表时间：
2015
影响因子：
--
通讯作者：
Liu Y
中科院分区：
文献类型：
--
作者：
Lv X;Zhao S;Ning Z;Zeng H;Shu Y;Tao O;Xiao C;Lu C;Liu Y
柑橘类水果在世界范围内种植，被认为是能量、营养和保健品消耗最高的水果之一。更重要的是，其中许多水果已在一些亚洲国家用作传统草药来治疗疾病。近几十年来，许多研究都集中在柑橘次生代谢物和生物活性上，并旨在开发新的化疗或补充药物。柑橘衍生的次生代谢物，包括类黄酮、生物碱、柠檬苦素、香豆素、类胡萝卜素、酚酸和精油，由于其活性特性对人类健康至关重要。这些特性包括抗氧化、抗炎、抗癌，以及心血管保护作用、神经保护作用等。本文总结了柑橘类水果的全球分布和分类、众多的次生代谢产物和生物活性，为进一步研究提供参考。主要介绍了柑橘类水果中特有的生物活性代谢物黄酮类化合物。本文的在线版本 (doi:10.1186/s13065-015-0145-9) 包含补充材料，可供授权用户使用。
Citrus fruits, which are cultivated worldwide, have been recognized as some of the most high-consumption fruits in terms of energy, nutrients and health supplements. What is more, a number of these fruits have been used as traditional medicinal herbs to cure diseases in several Asian countries. Numerous studies have focused on Citrus secondary metabolites as well as bioactivities and have been intended to develop new chemotherapeutic or complementary medicine in recent decades. Citrus-derived secondary metabolites, including flavonoids, alkaloids, limonoids, coumarins, carotenoids, phenolic acids and essential oils, are of vital importance to human health due to their active properties. These characteristics include anti-oxidative, anti-inflammatory, anti-cancer, as well as cardiovascular protective effects, neuroprotective effects, etc. This review summarizes the global distribution and taxonomy, numerous secondary metabolites and bioactivities of Citrus fruits to provide a reference for further study. Flavonoids as characteristic bioactive metabolites in Citrus fruits are mainly introduced. The online version of this article (doi:10.1186/s13065-015-0145-9) contains supplementary material, which is available to authorized users.