Establishing the incidence and timing of hypoglycemia at a residential diabetes camp.
Establishing the incidence and timing of hypoglycemia at a residential diabetes camp.
复制标题
确定糖尿病营地中低血糖的发生率和时间。
DOI：
10.1016/j.diabres.2019.04.003
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发表时间：
2019
影响因子：
5.1
通讯作者：
Nathan,BrandonM
中科院分区：
文献类型：
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作者：
Mann,ElizabethA;Lunos,Scott;Carrel,Elijah;Omann,Trevor;Halper,Alyssa;Kogler,Anne;Miller,BradleyS;Sunni,Muna;Bellin,MelenaD;Nathan,BrandonM
目的在为期一周的儿童糖尿病社区训练营中确定低血糖的发生率和发生时间。方法225名儿童(平均年龄12.0 ± 2.3mol，女性56%，平均血红蛋白8.4%[71.6mmoL/ ])在餐前、睡前和检测低血糖所需的情况下测定血糖(BG)。结果90%的露营者发生轻度低血糖(BG50~69 mg/dL[3.9 /L])， ≥ 1次，43%发生 ≥ 1次BG <； 50 mg/dL(2.8 /L)。没有出现需要胰高血糖素的低血糖事件。与本周晚些时候相比，露营者在夏令营的前48个 ≥ 小时内经历了更多的 -1过夜低血糖事件(p = 0.01)。夜间全营比赛不会在一夜之间影响低血糖发生率。结论夜间低血糖在前两个晚上发生得更频繁，将这段时间确定为高风险，并支持实施降低胰岛素剂量的标准方案。低血糖发生率不受全阵营游戏的影响，这表明目前的做法在将低血糖降至最低方面是有效的。
AimsTo establish the incidence and timing of hypoglycemia at a week-long residential diabetes camp for children. We hypothesized that hypoglycemia would occur more frequently during the first two days of camp and following evening all-camp games.Methods225 children (mean age 12.0 ± 2.3 years, 56% female, mean hemoglobin A1c 8.4% [71.6 mmol/mol]) had blood glucose (BG) levels obtained before meals, at bedtime, and as needed to detect hypoglycemia. Insulin adjustments were made by medical staff according to camp protocol and at the discretion of medical staff during camper check-in.ResultsMild hypoglycemia (BG 50–69 mg/dL [3.9 mmol/L]) occurred ≥ 1 time in 90% of campers while 43% had ≥ 1 episode of BG < 50 mg/dL (2.8 mmol/L). No episodes of hypoglycemia requiring glucagon occurred. More campers experienced ≥ 1 overnight hypoglycemia event during the first 48 hours of camp compared to later in the week (p = 0.01). Evening all-camp games did not impact hypoglycemia rates overnight.ConclusionsNocturnal hypoglycemia occurred more frequently during the first two nights, establishing this period as high risk and supporting implementation of a standard protocol to lower insulin doses. Rates of hypoglycemia were unaffected by all-camp games, indicating current practices are effective at minimizing hypoglycemia.