Pneumococcus: the first one hundred years.
Pneumococcus: the first one hundred years.
复制标题
肺炎球菌：第一个一百年。
DOI：
--
复制
发表时间：
1981
期刊：
影响因子：
--
通讯作者：
R. Austrian
中科院分区：
文献类型：
--
作者：
R. Austrian
本文简要回顾了肺炎球菌（肺炎链球菌）及其引起的疾病的研究在其最初分离后的一个世纪中对生物学和医学的一些主要贡献。讨论的主题包括细胞和体液对肺炎球菌感染的防御，肺炎球菌在定量免疫化学发展中的作用，肺炎球菌在识别细菌耐药性中的历史地位，以及这种生物在分子遗传学和分子生物学起源中所起的基本作用。由于在过去的100年里已经获得了大量关于肺炎球菌的知识，人们希望这些知识将继续增长，并作为扩展对细菌细胞和感染过程理解的基础。
Some of the major contributions to biology and medicine resulting from studies of the pneumococcus (Streptococcus pneumoniae) and of the diseases caused by it in the century following its initial isolation are reviewed briefly. Among the topics considered are cellular and humoral defenses against pneumococcal infection, the role of pneumococcus in the development of quantitative immunochemistry, the historical position of the pneumococcus in the recognition of bacterial resistance to drugs, and the fundamental role played by this organism in the origins of molecular genetics and molecular biology. Because of the vast store of knowledge of the pneumococcus that has been acquired in the past 100 years, the hope is expressed that this knowledge will continue to grow and to serve as a basis for the extension of understanding both the bacterial cells and of the processes of infection.