Decreased sperm motility is associated with air pollution in Salt Lake City
Decreased sperm motility is associated with air pollution in Salt Lake City
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DOI：
10.1016/j.fertnstert.2008.12.089
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发表时间：
2010-04-01
影响因子：
6.7
通讯作者：
Peterson, C. Matthew
中科院分区：
文献类型：
--
作者：
Hammoud, Ahmad;Carrell, Douglass T.;Peterson, C. Matthew
目的：研究空气污染指数与精子参数之间的相关性。设计：生态学研究。设置：包含的地理区域。患者：进行精液分析或人工授精的居民男性。干预措施：空气微粒污染水平分析（颗粒物[PM] 2.5）超过5-年期间与从精液分析获得的精子参数的关系以及分别与人工授精精液制备时精子参数的序列的关系。为了解释精子发生的持续时间（72天），通过将每个精液参数向后移动1、2、3和4个月来创建“校正”变量。最后的分析校正了一年中的季节和当前的温度。主要结果测量：精子浓度，精子活力和精子形态。结果：该研究包括1,699次精液分析和877次授精。PM 2.5水平在冬季最高，当时环境温度最低。精液分析数据显示，PM 2.5值与精子活力呈负相关，两个月和三个月后记录的PM 2.5值。人工授精数据也表明，精子活力与PM 2.5值呈负相关记录three months previous. Conclusions（S）：精液分析和精子参数数据从男性提出多次授精随着时间的推移表明，空气污染与精子活力降低两到三个月后曝光。（Fertil Steril（R）2010;93：1875-9. (C)美国生殖医学会（American Society for Reproductive Medicine）
Objective: To study the correlation between indices of air pollution and sperm parameters.Design: Ecological study.Setting: Contained geographic area.Patient(s): Resident men presenting for semen analysis or artificial insemination.Intervention(s): Analysis of levels of particulate air pollution (particulate matter [PM] 2.5) over a five-year period in relation to sperm parameters obtained from semen analyses and separately in relation to sequences of sperm parameters at the time of semen preparations for artificial insemination. To account for the duration of spermatogenesis (72 days), "corrected" variables were created by shifting backward 1, 2, 3 and 4 months each of the semen parameters. The final analysis corrected for season of the year and current temperature.Main Outcome Measure(s): Sperm concentration, sperm motility and sperm morphology.Result(s): The study included 1,699 semen analyses and 877 inseminations. PM 2.5 levels were highest in the winter months, when the ambient temperature was the lowest. Semen analysis data showed that values of PM 2.5 were negatively correlated to sperm motility two months and three months following the recording of the PM 2.5 values. Artificial insemination data also showed that sperm motility correlated negatively with PM 2.5 values recorded three months previously.Conclusion(s): Both semen analysis and sperm parameters data obtained from men presenting for multiple inseminations over time showed that air pollution is associated with reduced sperm motility two to three month after exposure. (Fertil Steril(R) 2010;93:1875-9. (C) 2010 by American Society for Reproductive Medicine.)