Economic Hardship, Ocular Complications, and Poor Self-reported Visual Function are Predictors of Mental Problems in Patients with Uveitis
Economic Hardship, Ocular Complications, and Poor Self-reported Visual Function are Predictors of Mental Problems in Patients with Uveitis
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经济困难、眼部并发症和自我报告的视觉功能不佳是葡萄膜炎患者精神问题的预测因素
DOI：
10.1080/09273948.2020.1770297
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发表时间：
2020-07-12
影响因子：
3.3
通讯作者：
Wang, Yuqin
中科院分区：
文献类型：
--
作者：
Jin, Yingying;Lin, Dan;Wang, Yuqin
摘要目的：了解葡萄膜炎患者的生活质量和心理健康状况，探讨心理问题的预测因素。方法：共有245例患者和105名对照者参加了这项横断面研究。生活质量，心理状态，社会人口学和临床数据从问卷和病历中获得。采用多元回归分析和受试者工作特征（ROC）分析方法，建立患者心理问题的预测模型。结果：在245例患者中，16.7%和26.5%（P<0.0001）的焦虑和抑郁筛查阳性。预测焦虑的模型包括低家庭年收入和自报的视觉功能差（分别为P=.029，P < .0001），ROC曲线下面积为0.744。预测抑郁症的模型包括自我报告的视觉功能差和眼部并发症（分别为P< .0001，P= .012），AUC为0.78。结论：经济困难、眼部并发症和自我报告的视觉功能差是葡萄膜炎患者出现精神问题的预测因素。
ABSTRACT Purpose: To characterize the quality of life and mental health status of patients with uveitis and investigate predictors of psychological problems. Methods: A total of 245 patients and 105 controls were enrolled in this cross-sectional study. Quality of life, psychological status, socio-demographic and clinical data were obtained from questionnaires and medical records. Multivariate regression analyses and Receiver Operating Characteristic (ROC) were applied to obtain the model predicting psychological problems of patients. Results: Of 245 patients, 16.7% and 26.5% (P< .0001) screened positive for anxiety and depression, respectively. The model predicting anxiety was comprised of low annual household income and poor self-reported visual function (P= .029,P< .0001, respectively), with an AUC of ROC of 0.744. The model predicting depression was comprised of poor self-reported visual function and ocular complications (P< .0001, P= .012, respectively), with an AUC of 0.78. Conclusions: Economic hardship, ocular complications, and poor self-reported visual function are predictors of mental problems in patients with uveitis.