The somatosensory representation of the human clitoris: An fMRI study
The somatosensory representation of the human clitoris: An fMRI study
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DOI：
10.1016/j.neuroimage.2009.07.024
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发表时间：
2010-01-01
期刊：
影响因子：
5.7
通讯作者：
Kollias, Spyros
中科院分区：
文献类型：
--
作者：
Michels, Lars;Mehnert, Ulrich;Kollias, Spyros
我们使用阴蒂背神经电刺激和功能磁共振成像研究了 15 名健康成年女性受试者阴蒂神经产生的阴部传入神经的中枢表征。作为控制身体区域，我们对八名受试者的右侧拇趾进行了电刺激。在区块设计实验中，我们应用了双侧阴蒂刺激和单侧（右）拇趾刺激。计算激活图来对比“阴蒂背神经刺激与休息”和“拇趾电刺激与休息”的对比。阴蒂刺激的随机效应组分析显示，双侧额叶回、岛叶和壳核，以及中央后回、中央前回和顶下回（包括初级和次级体感皮质）均有显着激活。中央后回的近中表面没有发现激活。对于拇趾，激活发生在类似的神经元网络中，但初级体感皮层的激活位于半球间裂中。这项研究的结果表明，来自阴蒂神经的阴部传入神经和来自拇趾的感觉输入的中央表征可以通过功能磁共振成像来研究和区分。根据体感小人描述的体位顺序，我们可以预期阴蒂神经电刺激会激活中央后回的内侧壁。相反，我们发现中央后回侧面有激活。 (c) 2009 Elsevier Inc. 保留所有权利。
We studied the central representation of pudendal afferents arising from the clitoral nerves in 15 healthy adult female subjects using electrical dorsal clitoral nerve stimulation and fMRI. As a control body region, we electrically stimulated the right hallux in eight subjects. In a block design experiment, we applied bilateral clitoral stimulation and unilateral (right) hallux stimulation. Activation maps were calculated for the contrasts electrical dorsal clitoral nerve stimulation versus rest' and 'electrical hallux Stimulation versus rest'. A random-effect group analysis for the clitoral stimulation showed significant activations bilateral in the superior and inferior frontal gyri, insulae and putamen and in the postcentral, precentral and inferior parietal gyri (including the primary and secondary somatosensory cortices). No activation was found on the mesial surface of the postcentral gyrus. For the hallux, activations occurred in a similar neuronal network but the activation in the primary somatosensory cortex was localized in the inter-hemispheric fissure. The results of this study demonstrate that the central representation of pudendal afferents arising from the clitoral nerves and sensory inputs from the hallux can be studied and distinguished from each other by fMRI. From the somatotopic order described in the somatosensory homunculus one would expect for electrical clitoral nerve stimulation activation of the mesial wall of the postcentral gyrus. In contrast, we found activations on the lateral surface of the postcentral gyrus. (c) 2009 Elsevier Inc. All rights reserved.