Retinal pigment epithelial cells: Biological property and application in Parkinson's disease
Retinal pigment epithelial cells: Biological property and application in Parkinson's disease
复制标题
DOI：
10.1097/00029330-200703010-00014
复制
发表时间：
2007-03-05
影响因子：
6.1
通讯作者：
Le Wei-dong
中科院分区：
文献类型：
--
作者：
Ming Ming;Le Wei-dong
帕金森病的治疗策略包括药物治疗和手术治疗。药物治疗是帕金森病的主要治疗方法，包括多巴胺补充药物、3多巴胺再摄取抑制剂、多巴胺能激动剂、4和毒蕈碱类拮抗剂。但这些药物也存在一些缺陷。例如，左旋多巴治疗通常与运动反应波动和运动障碍有关，而且大多数药物不能阻止疾病的进展。
Therapeutic strategy for Parkinson’s disease includes pharmacological therapy2 and surgical therapy. Pharmacological therapy is the main treatment for Parkinson’s disease, which includes dopamine supplementing drugs, 3 dopamine reuptake inhibitor, dopaminergic agonists, 4 and muscarinic antagonists. But there are some drawbacks existing in these drugs. For example, L-dopa treatment is often associated with fluctuations of motor response and dyskinesias, 5 and most drugs do not halt the progression of the disease.