Sexual risk behaviour and knowledge of HIV status among community samples of gay men in the UK
Sexual risk behaviour and knowledge of HIV status among community samples of gay men in the UK
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DOI：
10.1097/qad.0b013e3282f8af9b
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发表时间：
2008-05-31
期刊：
影响因子：
3.8
通讯作者：
Johnson, Anne M.
中科院分区：
文献类型：
--
作者：
Williamson, Lisa M.;Dodds, Julie P.;Johnson, Anne M.
目标：未确诊的感染存在进一步传播艾滋病毒的潜在风险，并使男性无法对其健康进行早期干预。人们对英国了解和不了解自己艾滋病毒感染状况的男性之间的差异知之甚少。方法：对伦敦、布莱顿、曼彻斯特、格拉斯哥和爱丁堡商业同性恋场所的男性进行横断面调查（2003-2005）。从 3672 名男性（61% 的回复率）中获取了匿名、自行填写的问卷和口腔液样本（检测 HIV 抗体）。结果：在 3501 名口腔液结果确诊为阳性或阴性的男性中，318 人为 HIV 阳性（9.1%）。其中，131 例（41.2%）未确诊； 81.1% 的未确诊艾滋病毒男性之前曾接受过检测（92.2% 检测结果呈阴性；其余人不知道结果）； 62.3%的人仍然认为自己持否定态度。未确诊和确诊的男性比艾滋病毒阴性男性有更高的性风险和性传播感染。与 HIV 阴性男性相比，未确诊男性与两个或更多伴侣进行无保护肛交的调整比值比在未确诊男性中较高（比值比 2.21，95% 置信区间 1.17-4.20），但在确诊男性中最高（比值比 6.80，95% 置信区间 4.39-10.52）。没有接受临床护理的好处，但在了解自己艾滋病毒呈阳性状况的男性中，性风险和性传播感染最高。诊所应主动提供检测，以减少未确诊的艾滋病毒，针对先前检测呈阴性的高危男性进行重复检测，并启动循证行为干预措施，以降低艾滋病毒确诊男性和检测呈阴性的男性的性风险。 (C) 2008 年 Wolters Kluwer Health 垂直条 Lippincott Williams & Wilkins。
Objectives: Undiagnosed infection presents a potential risk for the onward transmission of HIV and denies men early interventions for their health. Little is known about the differences between men who are, and are not, aware of their HIV status in the UK.Methods: Cross-sectional surveys of men in commercial gay venues in London, Brighton, Manchester, Glasgow, and Edinburgh (2003-2005). Anonymous, self-completion questionnaires, and oral fluid samples (tested for HIV antibodies) were obtained from 3672 men (61 % response rate).Results: Of 3501 men with a confirmed positive or negative oral fluid result, 318 were HIV positive (9.1%). Of these, 131 (41.2%) were undiagnosed; 81.1% of men with undiagnosed HIV had previously tested (92.2% tested negative; the remainder did not know the result); 62.3% still thought that they were negative. Undiagnosed and diagnosed men reported greater sexual risk and sexually transmitted infections than HIV-negative men. Compared with HIV-negative men, the adjusted odds ratio of unprotected anal intercourse with two or more partners was higher among undiagnosed men (odds ratio 2.21, 95% confidence interval 1.17-4.20), but highest among diagnosed men (odds ratio 6.80, 95% confidence interval 4.39-10.52).Conclusion: A high proportion of the HIV-positive men were undiagnosed and not receiving benefits of clinical care, but sexual risk and sexually transmitted infections were highest among men who were aware of their HIV-positive status. Clinics should proactively offer testing to reduce undiagnosed HIV, target repeat testing at high-risk men who have previously tested negative, and initiate evidence-based behavioural interventions to reduce sexual risk among men living with diagnosed HIV as well as those testing negative. (C) 2008 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.