A TOF-PET prototype with position sensitive PMT readout
A TOF-PET prototype with position sensitive PMT readout
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DOI：
10.1088/1674-1137/35/1/013
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发表时间：
2011
影响因子：
3.6
通讯作者：
Jin-da Chen;Hushan Xu;Zheng-guo Hu;R. F. Chen;B. Tang;K. Yue;Yu-hong Yu-Yu-hong-Yu-92418664;Xue-Heng Zhang;J. Kong;Y. Zang;Jian-song Wang;Zhili Sun;Zhong-yan Guo
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文献类型：
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作者：
Jin-da Chen;Hushan Xu;Zheng-guo Hu;R. F. Chen;B. Tang;K. Yue;Yu-hong Yu-Yu-hong-Yu-92418664;Xue-Heng Zhang;J. Kong;Y. Zang;Jian-song Wang;Zhili Sun;Zhong-yan Guo
研制了一台能同时探测正电子湮没产生的511 keV γ射线的飞行时间正电子发射计算机断层成像（TOF-PET）样机。它由两个80.5mm × 80.5mm的LYSO闪烁体阵列（由35 ×35像素的指状晶体组成）组成，位置敏感光电倍增管R2487作为读出器。每个阵列由2 mm ×2 mm×15 mm的指状晶体组成，平均像素间距为2.30 mm。测量结果表明，TOF信息可以显著改善图像重建中的噪声方差，从而提高图像质量。样机对511 keV γ射线的最佳空间分辨率（FWHM）在x和y方向上分别为1.98 mm和2.16 mm，小于平均像素间距2.30 mm。
A prototype of time-of-flight positron emission computed tomography (TOF-PET) has been developed for acquiring the coincident detection of 511 keV γ-rays produced from positron annihilation. It consists of two 80.5 mm×80.5 mm LYSO scintillator arrays (composed of 35 ×35 pixel finger crystals) with the position sensitive photomultiplier tubes R2487 as the readout. Each array is composed of 2 mm ×2 mm×15 mm finger crystals and the average pixel pitch is 2.30 mm. The measured results indicate that the TOF information has the potential to significantly enhance the image quality by improving the noise variance in the image reconstruction. The best spatial resolution (FWHM) of the prototype for the pairs of 511 keV γ-rays is 1.98 mm and 2.16 mm in the x and y directions, respectively, which are smaller than the average pixel pitch of 2.30 mm.