Ratio of low serum zinc levels in elderly Japanese people living in the central part of Japan
Ratio of low serum zinc levels in elderly Japanese people living in the central part of Japan
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DOI：
10.1038/sj.ejcn.1602520
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发表时间：
2007-03-01
影响因子：
4.7
通讯作者：
Yamamoto, S.
中科院分区：
文献类型：
--
作者：
Kogirima, M.;Kurasawa, R.;Yamamoto, S.
目的：老年患者常出现味觉减退、恶心、食欲不振、褥疮延迟愈合等症状。在许多这些患者中，血清锌水平低，他们对锌补充剂有反应。到目前为止，日本还没有缺锌流行病的报告。我们研究了锌缺乏症的患病率及其致病因素，在一个典型的当地城镇在Japan.Design：横断面研究。设置：长野县（日本中部）。主题和方法：血清锌水平测定1009居民（18 - 96岁）谁参加了2003年的年度大规模健康检查计划的城市。在所有受试者中，随机选择86名血清锌水平低（< 65 μ g/dl）或高（>= 90 μ g/dl）的受试者，并于2004年采用24小时回顾法进行了连续2天的膳食调查。结果：老年人（≥ 60岁）中血清锌水平低于美国标准第2.5百分位数者占37.9%;在老年人群中，低血清锌的年龄调整患病率为21.1%。老年人（>= 60岁）锌摄入量与血清锌水平呈正相关。结论：日本中部成年居民锌缺乏的可能性随年龄增长而增加。锌缺乏与膳食锌摄入量有关。
Objective: Elderly patients often have impaired taste, nausea, anorexia and delayed healing of decubitus. In many of these patients, serum zinc levels are low and they respond to zinc supplementation. To date, no epidemics of zinc deficiency have been reported in Japan. We studied the prevalence of zinc deficiency and its causative factors in a typical local town in Japan.Design: Cross-sectional study.Setting: Nagano Prefecture ( central Japan).Subjects and methods: Serum zinc levels were measured in 1009 habitants (18 - 96 years old) who participated in an annual mass health examination program of the City in 2003. Of all subjects, 86 with low serum zinc (< 65 mu g/dl) or high zinc (>= 90 mu g/dl) levels were randomly selected, and a dietary survey using 24-h recalling methods for 2 consecutive days was performed in 2004. Among them, blood was collected in the morning from 50 subjects ( 26 - 94 years old).Results: The percentage of those with low serum zinc levels (2.5th percentile of Americans) was 37.9% in the elderly (>= 60 years old). The age-adjusted prevalence of low serum zinc was 21.1% in the aged population. A positive correlation was detected between zinc intake and serum zinc levels in elderly subjects (>= 60 years old).Conclusions: The possibility of zinc deficiency in adult inhabitants in central Japan rises with age. The deficiency correlates with dietary zinc intake.