TBtools: An Integrative Toolkit Developed for Interactive Analyses of Big Biological Data

TBtools: An Integrative Toolkit Developed for Interactive Analyses of Big Biological Data
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TBtools:为生物大数据交互式分析而开发的综合工具包

DOI:
10.1016/j.molp.2020.06.009
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发表时间:
2020-08-03
期刊:
影响因子:
27.5
通讯作者:
Xia, Rui
Xia, Rui
中科院分区:
生物学1区
文献类型:
--
作者:
Chen, Chengjie;Chen, Hao;Xia, Rui

文献摘要

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高通量测序技术的快速发展将生物学带入了大数据时代。使用各种生物信息学工具进行数据分析依赖于编程和命令行环境,这对大多数湿实验室生物学家来说是具有挑战性和耗时的。在这里,我们介绍了TBtools(一个集成了各种生物数据处理工具的生物学家工具包),这是一个具有用户友好界面的独立软件。该工具包包含130多个功能,旨在满足日益增长的大数据分析需求,从批量序列处理到交互式数据可视化。使用新的绘图引擎(“JIGplot”),可以在TBtools中准备各种各样的图形,以最大限度地提高其交互能力;这个引擎允许快速点击修改几乎每一个图形特性。TBtools是独立于平台的软件,可以在使用Java Runtime Environment 1.6或更新版本的所有操作系统下运行。它是免费提供给非商业用户在https://github.com/CJ-Chen/TBtools/releases。
The rapid development of high-throughput sequencing techniques has led biology into the big-data era. Data analyses using various bioinformatics tools rely on programming and command-line environments, which are challenging and time-consuming for most wet-lab biologists. Here, we present TBtools (a Toolkit for Biologists integrating various biological data-handling tools), a stand-alone software with a user-friendly interface. The toolkit incorporates over 130 functions, which are designed to meet the increasing demand for big-data analyses, ranging from bulk sequence processing to interactive data visualization. A wide variety of graphs can be prepared in TBtools using a new plotting engine ("JIGplot") developed to maximize their interactive ability; this engine allows quick point-and-click modification of almost every graphic feature. TBtools is platform-independent software that can be run under all operating systems with Java Runtime Environment 1.6 or newer. It is freely available to non-commercial users at https://github.com/CJ-Chen/TBtools/releases.