The effect of the COVID-19 pandemic on the treated incidence of psychotic disorders in South London.
The effect of the COVID-19 pandemic on the treated incidence of psychotic disorders in South London.
复制标题
COVID-19 大流行对伦敦南部精神障碍治疗发病率的影响。
DOI：
10.1016/j.psychres.2023.115483
复制
发表时间：
2023
影响因子：
11.3
通讯作者：
Spinazzola E
中科院分区：
文献类型：
--
作者：
Spinazzola E
到目前为止，有关COVID-19大流行对精神障碍影响的证据尚不多见。我们进行了一项发病率研究，以确定伦敦南部在COVID-19大流行之前和期间的首发精神病（FEP）发病率。我们筛选了居住在伦敦萨瑟克和兰贝斯区的个人的临床记录，这些人之前被转介到早期干预服务。于2019年1月3日至2020年2月28日期间）及2020年1月3日至2021年2月28日期间（2019冠状病毒病大流行期间）。我们使用国家统计局来确定处于危险中的人口。我们计算了每10万人年的粗略和性别-年龄标准化FEP发病率。我们使用泊松回归计算了COVID-19大流行期间的发病率比（IRR）。在COVID-19大流行期间，共确定了321例FEP事件病例，占每10万人年69.8（95%CI 62.1-77.4）的粗发病率。前一年的粗发病率为47.5（95% CI 41.2-53.8）。两年之间的发生率变化导致调整后的IRR为1.45（95% CI 1.22-1.72）。大流行伴随着首次精神病发作率的45%飙升。这一发现应该为公共卫生研究提供信息，并表明需要为二级保健提供足够的资源。
Evidence on the impact of the COVID-19 pandemic on psychotic disorders is so far scarce. We conducted an incidence study to ascertain rates of first-episode psychosis (FEP) before and during the COVID-19 pandemic in South London.We screened clinical records of individuals living in the London boroughs of Southwark and Lambeth who were referred to the early intervention services before (from 1/3/2019 to 28/2/2020) and during (from 1/3/2020 to 28/2/2021) the COVID-19 pandemic. We used the Office for National Statistics to determine the population at risk. We computed crude and sex-age standardised FEP incidence per 100,000 person-years. We used Poisson regression to calculate the incidence rate ratio (IRR) across the COVID-19 pandemic.A total of 321 incident cases of FEP were identified during the COVID-19 pandemic, accounting for a crude rate of 69.8 (95% CI 62.1–77.4) per 100,000 person-years. The crude rate for the year before was 47.5 (95% CI 41.2–53.8). The incidence variation between the two years accounted for an adjusted IRR of 1.45 (95% CI 1.22–1.72). The pandemic was accompanied by a 45% spike in the rates of first-episode psychosis. This finding should inform public health research and demonstrate the need for adequate resources for secondary care.