Effect of low-level clenching and subsequent muscle pain on exteroceptive suppression and resting muscle activity in human jaw muscles.
Effect of low-level clenching and subsequent muscle pain on exteroceptive suppression and resting muscle activity in human jaw muscles.
复制标题
低水平咬紧牙关和随后的肌肉疼痛对人类下颌肌肉的外感受抑制和静息肌肉活动的影响。
DOI：
10.1016/j.clinph.2006.11.311
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发表时间：
2007
期刊：
影响因子：
--
通讯作者：
Arendt-Nielsen,Lars
中科院分区：
文献类型：
--
作者：
Torisu,Tetsurou;Wang,Kelun;Svensson,Peter;DeLaat,Antoon;Fujii,Hiroyuki;Arendt-Nielsen,Lars
目的探讨低水平等长咬紧牙关引起的肌肉疲劳和随后的谷氨酸诱发的肌肉疼痛对人类下颌肌肉的外感受抑制（ES）反应和静息肌电（EMG）活动的影响。方法记录低水平咬紧牙关前（基线）、低水平咬紧牙关后（后1）、随后向左侧注射谷氨酸或等渗盐水后的静息肌电图活动和ES。 23名健康志愿者的咬肌（Post2）和咬紧后60分钟（Post3）。结果与基线相比，晚期ES（ES2）在Post1表现出更多的抑制（P<0.05）。在两种类型的注射后（Post2），其抑制程度较小，并在 Post3 再次增加（P<0.05），谷氨酸和等渗盐水疗程之间没有显着差异。 Post1和Post2时静息肌电图活动增加（P<0.05）。谷氨酸注射进一步增加了注射肌肉的静息肌电图活动（P<0.01）。结论肌肉疲劳影响颌闭合肌肉的抑制反射通路，随后的急性肌肉疼痛增强了疼痛肌肉静息肌电图活动的局部增加。意义口腔功能障碍患者中观察到的肌肉疲劳可能与伤害性调节相互作用，并影响颌症状和功能的临床表现。
OBJECTIVETo investigate the effects of muscle fatigue induced by low-level isometric jaw-clenching and subsequent glutamate-evoked muscle pain on the exteroceptive suppression (ES) response and resting electromyographic (EMG) activities in human jaw muscles.METHODSThe resting EMG activity and the ESs were recorded before (baseline), after low-level jaw-clenching (Post1), after subsequent glutamate or isotonic saline injections into the left masseter (Post2), and 60min after the clenching (Post3) in 23 healthy volunteers.RESULTSThe late ES (ES2) showed more inhibition at Post1 compared with baseline (P<0.05). It was less inhibited after both types of injections (Post2), and increased at Post3 again (P<0.05) with no significant difference between the glutamate and isotonic saline sessions. The resting EMG activity increased at Post1 and Post2 (P<0.05). The glutamate injection further increased the resting EMG activity in the injected muscle (P<0.01).CONCLUSIONSMuscle fatigue influences inhibitory reflex pathways in jaw-closing muscles and subsequent acute muscle pain potentiates the local increase in the resting EMG activity of the painful muscle.SIGNIFICANCEMuscle fatigue which can be observed in patients with oral dysfunctions may interact with nociceptive regulation and influence the clinical presentation of jaw symptoms and function.