JOINT COORDINATION DEFICITS IN LIMB APRAXIA
JOINT COORDINATION DEFICITS IN LIMB APRAXIA
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DOI：
10.1093/brain/118.1.227
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发表时间：
1995-02-01
期刊：
影响因子：
14.5
通讯作者：
HEILMAN, KM
中科院分区：
文献类型：
--
作者：
POIZNER, H;CLARK, MA;HEILMAN, KM
通过分析三名患有包括左顶叶在内的失用症受试者的关节协调缺陷，测试了肢体失用症基础的竞争模型。记录了在一系列条件下重复“切片”手势的三维肩肘、手腕和手部轨迹，其中以分级方式引入上下文线索。失用的受试者在跨环境条件下的联合协调方面表现出明显的缺陷。即使在实际操作工具和物体时，失用的受试者也无法表现出适当的关节同步，无法正确分配其相对关节幅度，并且无法在手臂角度对之间产生正确的相位关系。因此，失用者不仅在运动的空间规划上存在缺陷，而且在将这些辫子转化为关节角运动的细节方面也存在缺陷，即使在实际操作工具和物体时也是如此。这些数据支持失用症模型，其中失用症可能是由于存储在后联皮层中的习得运动的视觉动觉运动表征的破坏，或者是这些表征与前运动区或运动区的分离造成的。
Competing models of the basis of limb apraxia were tested through analysis of joint coordination deficits in three apraxic subjects with lesions that included the left parietal lobe. Three-dimensional shoulder elbow, wrist and hand trajectories were recorded for repetitive 'slicing' gestures made in a series of conditions in which contextual cues were introduced in a graded fashion. The apraxic subjects showed marked deficits in joint coordination across context conditions. Even when actually manipulating a tool and object, the apraxic subjects failed to show proper joint synchronization, failed to apportion their relative joint amplitudes properly, and failed to produce the correct phase relationships among pairs of arm angles. Thus, apraxic subjects not only have deficits in the spatial plan for the movement, but they also have deficits in translating those plaits into the details of the angular motions at the joints, even when actually manipulating a tool and object. These data support a model of apraxia in which apraxia can result from either the destruction of visuo-kinaesthetic motor representations of learned movement, stored in posterior association cortex, or from a separation of these representations from premotor or motor areas.