Picture-Based Memory Impairment Screen for Dementia
Picture-Based Memory Impairment Screen for Dementia
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DOI：
10.1111/j.1532-5415.2012.04191.x
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发表时间：
2012-11-01
影响因子：
6.3
通讯作者：
Mathuranath, Pavagada S.
中科院分区：
文献类型：
--
作者：
Verghese, Joe;Noone, Mohan L.;Mathuranath, Pavagada S.
目的开发和验证一种基于图片的记忆障碍筛查（PMIS）用于检测痴呆症。设计横断面。设置门诊诊所，婴儿纪念医院，科泽科德市在印度南部的喀拉拉邦。参与者304名社区居民，年龄55至94岁，平均教育水平为8年; 65人被诊断为痴呆症。测量PMIS：这是一种由非专业人士进行的基于图片的文化公平认知筛查。PMIS评分在痴呆诊断中的准确性评估（敏感性、特异性、阳性和阴性预测能力）（范围0-8）。结果痴呆患者的PMIS评分（1.5）比对照组（7.7）差（P <0.001）。在最佳截分为5时，PMIS检测痴呆的敏感性为95.4%（95%置信区间（CI）= 90.3-100.0%），特异性为99.2%（95% CI = 98.0-100.0%）。在167名受教育程度< 10年的参与者中，PMIS评分为5或更低的敏感性为97.8%（95%CI = 93.6-100.0%），特异性为99.2%（95%CI = 97.6-100.0%）。PMIS有更好的特异性比简易精神状态检查在检测痴呆，特别是在老年人与低education.Conclusion的PMIS是一个简单而可靠的筛选老年人群中的痴呆与可变识字率。J Am Geriatr Soc 60：2116-2120，2012.
Objectives To develop and validate a picture-based memory impairment screen (PMIS) for the detection of dementia.Design Cross-sectional.Setting Outpatient clinics, Baby Memorial Hospital, Kozhikode city in the southern Indian state of Kerala.Participants Three hundred four community-residing adults aged 55 to 94 with a mean education level of 8 years; 65 were diagnosed with dementia.Measurements PMIS: a culture-fair picture-based cognitive screen designed to be administered by nonspecialists. Diagnostic accuracy estimates (sensitivity, specificity, positive and negative predictive power) of PMIS cut-scores in detecting dementia (range 0-8).Results PMIS scores were worse in participants with dementia (1.5) than in controls (7.7, P < .001). At the optimal cut-score of 5, PMIS had a sensitivity of 95.4% (95% confidence interval (CI) = 90.3-100.0%) and a specificity of 99.2% (95% CI = 98.0-100.0%) for detecting dementia. In the 167 participants with < 10 years of education, PMIS scores of five or less had a sensitivity of 97.8% (95% CI = 93.6-100.0%) and specificity of 99.2% (95% CI = 97.6-100.0%). The PMIS had better specificity than the Mini-Mental State Examination in detecting dementia, especially in older adults with low education.Conclusion The PMIS is a brief and reliable screen for dementia in elderly populations with variable literacy rates. J Am Geriatr Soc 60: 2116-2120, 2012.