Maternal ethanol exposure induces transient impairment of umbilical circulation and fetal hypoxia in monkeys.
Maternal ethanol exposure induces transient impairment of umbilical circulation and fetal hypoxia in monkeys.
复制标题
母体乙醇暴露会导致猴子脐带循环短暂受损和胎儿缺氧。
作者：
A. Mukherjee;G. Hodgen
当给怀孕的猴子静脉注射乙醇时，在大约15分钟内观察到短暂但明显的脐带血管塌陷。乙醇引起的脐带循环障碍导致胎儿严重缺氧和酸中毒；在接下来的一个小时里恢复了。这种显著的胎胎盘循环中断可能解释了智力低下的机制之一，智力低下是胎儿酒精综合征患儿的常见表现。
When ethanol was administered intravenously to pregnant monkeys, a transient but marked collapse of umbilical vasculature was observed uniformly within about 15 minutes. The ethanol-induced impairment of umbilical circulation produced severe hypoxia and acidosis in the fetus; recovery occurred during the succeeding hour. This striking interruption of feto-placental circulation may explain one of the mechanisms of mental retardation, a frequent manifestation in children afflicted with fetal alcohol syndrome.