The hypothalamic-pituitary-adrenal axis in alcoholics.
The hypothalamic-pituitary-adrenal axis in alcoholics.
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酗酒者的下丘脑-垂体-肾上腺轴。
DOI：
10.1111/j.1530-0277.1983.tb05408.x
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
Alan F. Schatzberg
中科院分区：
文献类型：
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作者：
Juan R. de La Fuente;Alan H. Rosenbaum;Robert M. Morse;Robert G. Niven;Charles F. Abboud;Nai;Alan F. Schatzberg
通过测定一组酒精中毒患者服用2 mg地塞米松前后的血浆皮质类固醇水平和尿游离皮质醇排泄量，研究了该组患者的下丘脑-垂体-肾上腺轴。患者最近戒酒，并被发现处于分泌过多状态。然而，轴似乎是完整的，因为他们能够抑制类固醇时，给予外源性。
The hypothalamic-pituitary-adrenal axis of a group of patients suffering from alcoholism was studied by determining their plasma corticosteroid levels and urinary-free cortisol excretion before and after administration of 2 mg of dexamethasone. The patients were recently abstinent from alcohol and were found to be in a hypersecretory state. However, the axis appeared to be intact because they were able to suppress when steroid was given exogenously.