The spread of activity in the cerebral cortex
The spread of activity in the cerebral cortex
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DOI：
10.1113/jphysiol.1936.sp003427
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发表时间：
1936-11-01
影响因子：
5.5
通讯作者：
Adrian, ED
中科院分区：
文献类型：
--
作者：
Adrian, ED
本文的主要目的是研究诸如给定的潜在变化揭示了什么样的皮质活动等问题；哪些结构负责电位变化，或者当大脑受到电刺激时，兴奋如何从一个神经元传播到另一个神经元，并且其活动不是通过四肢的运动记录的，而是通过其表面产生的动作电位记录的。这些观察是在麻醉下对兔子、猫和猴子进行的。对弱刺激的最简单的反应是潜在的变化，其中受刺激的区域变为负值至几毫米。离开。用更强的电流重复刺激会导致反应形式的变化。由于活性区域低于表面一定距离的元素，受激区域现在变为正值。
The main object of the present paper is to investigate such questions as what kind of cortical activity is revealed by a given potential change; what structures are responsible for the potential changes, or how excitations spread from one neurone to another, when the brain is stimulated electrically, and its activity recorded not by the movements of limbs, but by the action potentials developed at its surface. The observations were made on rabbits, cats and monkeys, under dial anesthesia. The simplest response to a weak stimulus is a potential change in which the stimulated region becomes negative to points a few mm. away. Repeated stimulation with stronger currents brings about a change in the form of the response. The stimulated region now becomes positive due to elements with the active region some distance below the surface.