On designing experiments for a dynamic response modeled by regression splines
On designing experiments for a dynamic response modeled by regression splines
复制标题
关于设计由回归样条建模的动态响应的实验
DOI:
10.1002/asmb.2490
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发表时间:
2020
影响因子:
1.4
通讯作者:
Saleh, Moein
中科院分区:
文献类型:
--
作者:
Pan, Rong;Saleh, Moein
Dynamic response systems are often found in science, engineering, and medical applications, but the discussion on experimental design for such a system is relatively rare in literature. For an experimenter, designing such experiments requires making decisions on (1) when or where to take response measurements along the dynamic variable and (2) how to choose the combination of experimental factors and their levels. The first consideration is unique for such experiments, especially when the measurement cost is high. In this paper, we present a design approach through the mixed‐effect linear model, which is based on a hierarchical B‐spline function for the dynamic response. We develop several theorems that can assist in finding a statistically efficient sampling plan and propose an algorithm for searching the D‐optimal design of a dynamic response system.
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Communications in statistics. Simulation and computation
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