FORMATION DE SULFITE, DACIDE CYSTEIQUE ET DE TAURINE A PARTIR DE SULFATE PAR LOEUF EMBRYONNE
FORMATION DE SULFITE, DACIDE CYSTEIQUE ET DE TAURINE A PARTIR DE SULFATE PAR LOEUF EMBRYONNE
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DOI：
10.1016/0006-3002(57)90102-6
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发表时间：
1957-01-01
期刊：
影响因子：
--
通讯作者：
FROMAGEOT, P
中科院分区：
文献类型：
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作者：
CHAPEVILLE, F;FROMAGEOT, P
在S35硫酸盐的帮助下，从胚胎卵子的硫酸盐开始研究牛磺酸的形成。以下反应发生：(1)硫酸盐还原成亚硫酸盐；(2)亚硫酸盐与氨基固定在三碳碳链上，这是半胱氨酸脱水生成L-半胱酸的结果；(3)L-半胱酸的脱羧基。反应(1)只发生在卵黄室细胞中；反应(2)发生在卵黄中；反应(3)发生在胚胎和卵黄中。作用于L-半胱酸的脱羧酶是一种专一性酶，其作用受半胱氨酸-亚磺酸的抑制。
The formation of taurine, starting from the sulfate of the embryonic egg, is studied with the aid of S35 sulfate. The following reactions occur (1) reduction of sulfate to sulfite; (2) fixation of the sulfite on a tricarbon chain with an amino group, resulting from the desulfhydration of cysteine, which leads to the formation of L-cysteic acid; (3) decarboxylation of the L-cysteic acid. Reaction (1) takes place solely in the vitelline chamber cells; reaction (2) in the yolk; reaction (3) in the embryo and yolk. The decarboxylase acting on the L-cysteic acid is a specific enzyme, the action of which is inhibited by cysteine-sulfinic acid.