The Na/K pump, Cl ion, and osmotic stabilization of cells

The Na/K pump, Cl ion, and osmotic stabilization of cells
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DOI:
10.1073/pnas.0931278100
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发表时间:
2003-05-13
影响因子:
11.1
通讯作者:
Armstrong, CM
Armstrong, CM
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Armstrong, CM

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An equation for membrane voltage is derived that takes into account the electrogenicity of the Na/K pump and is valid dynamically, as well as in the steady state. This equation is incorporated into a model for the osmotic stabilization of cells. The results emphasize the role of the pump and membrane voltage in lowering internal Cl- concentration, thus making osmotic room for vital substances that must be sequestered in the cell.