Initial Evaluation of Hemostasis: Reagent and Method Selection
Initial Evaluation of Hemostasis: Reagent and Method Selection
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止血的初步评估：试剂和方法的选择
DOI：
10.1002/9781118543467.ch9
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
W. Chandler
中科院分区：
文献类型：
--
作者：
W. Chandler
用于初步评价止血的试验用于帮助确定患者是否有任何临床显著的获得性或遗传性凝血因子缺陷的证据，最常见于出血患者，在侵入性手术前或开始抗血栓药物治疗前。初始评价包括凝血酶原时间（PT）、活化部分凝血活酶时间（aPTT）、纤维蛋白原、凝血酶时间和全血粘弹性测定的测量，用于手术期间止血的快速评价。本章帮助读者确定可能最有用的检测类型，然后详细回顾上述每项检测的仪器-试剂选择，然后总结每项检测建议的最低评估步骤。
Assays for the initial evaluation of hemostasis are used to help determine whether the patient has any evidence of a clinically significant acquired or hereditary deficiency of coagulation factors most often in patients that are bleeding, prior to invasive procedures or prior to starting anti‐thrombotic medications. The initial evaluation includes measurement of the prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen, thrombin time, and whole blood viscoelastic assays for the rapid evaluation of hemostasis during surgery. This chapter helps the reader determine the type of testing that may be most useful, then provides a detailed review of instrument‐reagent selection for each of the tests mentioned above followed by a summary of the minimum evaluation steps that are recommended for each test.